Evidence map›Paper›PMID 29325797›Full record

ArticleJournal of cardiac failure2018

Consequences of Retained Defibrillator and Pacemaker Leads After Heart Transplantation-An Underrecognized Problem.

Luise Holzhauser, Teruhiko Imamura, Hemal M Nayak, Nitasha Sarswat, Gene Kim, Jayant Raikhelkar, Sara Kalantari, Amit Patel, David Onsager, Tae Song and 4 more

Abstract read
In one paragraph

Article in Journal of cardiac failure, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Acute and chronic venous occlusion.The British journal of radiology · 2023
    Review
  5. Safety of MRI in patients with retained cardiac leads.Magnetic resonance in medicine · 2022
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Luise HolzhauserDivision of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois.
Teruhiko ImamuraDivision of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois.
Hemal M NayakDivision of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois.
Nitasha SarswatDivision of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois.
Gene KimDivision of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois.
Jayant RaikhelkarDivision of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois.
Sara KalantariDivision of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois.
Amit PatelDivision of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois.
David OnsagerDivision of Cardiothoracic Surgery, Department of Surgery, University of Chicago, Chicago, Illinois.
Tae SongDivision of Cardiothoracic Surgery, Department of Surgery, University of Chicago, Chicago, Illinois.
Takeyoshi OtaDivision of Cardiothoracic Surgery, Department of Surgery, University of Chicago, Chicago, Illinois.
Valluvan JeevanandamDivision of Cardiothoracic Surgery, Department of Surgery, University of Chicago, Chicago, Illinois.
Gabriel SayerDivision of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois.
Nir UrielDivision of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois. Electronic address: nuriel@medicine.bsd.uchicago.edu.

Funding

MULTIDISCIPLINARY CARDIAC SCIENCEST32HL007381 · NHLBI · UNIVERSITY OF CHICAGO · PI JEANNE M DECARA, Yoav Gilad · 1985 to 2026
$12.5M
NHLBI NIH HHS T32 HL007381
6 · The paper itself

Abstract

backgroundCardiovascular implantable electronic devices (CIEDs) are common in patients undergoing heart transplantation (HT), and complete removal is not always possible at the time of transplantation.

methodsWe retrospectively assessed the frequency of retained CIED leads and clinical consequences in consecutive HT patients from 2013 to 2016. Clinical outcomes included bacteremia, upper-extremity deep venous thrombosis (UEDVT), lead migration, and inability to perform magnetic resonance imaging (MRI).

resultsA total of 138 patients (55 ± 11 years of age, 76% male) were identified; 37 (27%) had retained lead fragments (RLFs) at discharge. Patients with RLFs were older, had longer lead implantation time before HT, and a higher prevalence of dual-coil CIED leads compared with those without RLFs (P < .05 for all). Lead implantation time was identified as an independent predictor for RLFs (P < .05). Patients with RLFs had a higher frequency of DVT compared with the non-RLF group during the 1-year study period (42% vs 21%; P < .04). There was no difference in bacteremia. Fourteen patients (38%) could not undergo clinically indicated MRI.

conclusionRLFs after HT occur commonly and are associated with a higher rate of UEDVT and limit the use of MRI. Although no significant difference was found in the rates of bacteremia between the groups, this finding might be explained by the overall low incidence. Patients with risk factors for RLFs should be identified before transplantation, and complete lead removal should be considered with a multidisciplinary approach.

Indexed as

Device RemovalHeart TransplantationRisk AssessmentDefibrillators, ImplantableFemaleFollow-Up StudiesHeart FailureHumansIllinoisIncidenceMagnetic Resonance Imaging, CineMaleMiddle AgedPacemaker, ArtificialPostoperative ComplicationsRetrospective Studiesdeep venous thrombosis (DVT)Heart transplantationmagnetic resonance imaging (MRI)retained ICD leads

Identifiers

PMID29325797
PMCPMC5945281

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.