Evidence map›Paper›PMID 29325452›Full record

ReviewBiological research for nursing2018

Inherited Cancer in the Age of Next-Generation Sequencing.

Kristin S Price, Ashley Svenson, Elisabeth King, Kaylene Ready, Gabriel A Lazarin

Open access · hybridAbstract readReview
In one paragraph

Review in Biological research for nursing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Treatment algorithm in patients with ovarian cancer.Facts, views & vision in ObGyn · 2020
    Article
  8. Wise Management of Ovarian Cancer: On the Cutting Edge.Journal of personalized medicine · 2020
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kristin S Price1 Counsyl, South San Francisco, CA, USA.
Ashley Svenson1 Counsyl, South San Francisco, CA, USA.
Elisabeth King2 Texas Oncology, Austin, TX, USA.
Kaylene Ready1 Counsyl, South San Francisco, CA, USA.
Gabriel A Lazarin1 Counsyl, South San Francisco, CA, USA.ORCID 0000-0001-5061-8595
Texas Oncology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Next-generation sequencing (NGS) technology has led to the ability to test for multiple cancer susceptibility genes simultaneously without significantly increasing cost or turnaround time. With growing usage of multigene testing for inherited cancer, ongoing education for nurses and other health-care providers about hereditary cancer screening is imperative to ensure appropriate testing candidate identification, test selection, and posttest management. The purpose of this review article is to (1) provide an overview of how NGS works to detect germline mutations, (2) summarize the benefits and limitations of multigene panel testing, (3) describe risk categories of cancer susceptibility genes, and (4) highlight the counseling considerations for patients pursuing multigene testing.

Indexed as

Genetic Predisposition to DiseaseHigh-Throughput Nucleotide SequencingFemaleGenetic TestingHumansMaleMutationNeoplasmshereditary cancer testinginherited cancermultigene panelnext-generation sequencing

Identifiers

PMID29325452
PMCPMC6030806
OpenAlexW2790143152

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.