Evidence map›Paper›PMID 29325238›Full record

ArticleThe Journal of clinical psychiatry

Psychometrics of the Self-Report Concise Associated Symptoms Tracking Scale (CAST-SR): Results From the STRIDE (CTN-0037) Study.

Joseph M Trombello, Michael O Killian, Allen Liao, Katherine Sanchez, Tracy L Greer, Robrina Walker, Bruce Grannemann, Chad D Rethorst, Thomas Carmody, Madhukar H Trivedi

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in The Journal of clinical psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01141608 (NIDA CTN Protocol 0037), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01141608 nacompletednot on this map

NIDA CTN Protocol 0037: Stimulant Reduction Intervention Using Dosed Exercise (STRIDE)

TypeinterventionalSponsorUniversity of Texas Southwestern Medical CenterRan2010 to 2013Enrolled302ConditionsStimulant Abuse and DependenceArmsVigorous Intensity High Dose Exercise, Health Education Intervention
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Joseph M TrombelloDepartment of Psychiatry, Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Michael O KillianSchool of Social Work, University of Texas at Arlington, Arlington, Texas, USA.
Allen LiaoDepartment of Psychiatry, Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Katherine SanchezSchool of Social Work, University of Texas at Arlington, Arlington, Texas, USA.
Tracy L GreerDepartment of Psychiatry, Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Robrina WalkerDepartment of Psychiatry, Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Bruce GrannemannDepartment of Psychiatry, Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Chad D RethorstDepartment of Psychiatry, Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Thomas CarmodyDepartment of Psychiatry, Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Madhukar H TrivediDepartment of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9119. madhukar.trivedi@utsouthwestern.edu.
The University of Texas at Arlington · US

Funding

Project-004UG1DA020024 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI Steven J Shoptaw, MADHUKAR H. TRIVEDI · 2015 to 2026
$71.6M
Concept ProjectU10DA020024 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI TRIVEDI, MADHUKAR H. · 2005 to 2015
$22.6M
An Exercise Intervention to Prevent Interferon-Induced Depression in Hepatitis CK01MH097847 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI RETHORST, CHAD D · 2013 to 2016
$595k
NIDA NIH HHS U10 DA020024NIDA NIH HHS UG1 DA020024NIMH NIH HHS K01 MH097847
6 · The paper itself

Abstract

objectiveThe self-report Concise Associated Symptoms Tracking Scale (CAST-SR) was developed to track mania, irritability, anxiety, panic, and insomnia symptoms among depressed outpatients receiving antidepressant medication. Given the overlap between these domains, depression, and stimulant use disorders, we reexamined CAST-SR psychometrics in a novel sample: individuals with stimulant use disorder receiving aerobic exercise or health education interventions.

methodsUsing the subsample of stimulant-dependent (following DSM-IV criteria) individuals prescribed antidepressants (N = 124) from the multisite Stimulant Reduction Intervention Using Dosed Exercise (CTN-0037) trial (total sample N = 302), conducted July 2010 to February 2013, we analyzed CAST-SR data collected at the first assessment after participant's discharge from residential treatment. We also evaluated the convergent/discriminant validity of the CAST-SR with several self-report questionnaires.

resultsConfirmatory factor analysis revealed a 12-item measure composed of 4 factors: irritability, anxiety, panic, and insomnia. This factor structure loaded only in participants prescribed antidepressant medication, not in those who were not prescribed antidepressants. These results replicate the original CAST-SR factor structure, except for the mania factor, which failed to load. Internal consistency was high (α = 0.92 for total scale and α = 0.78-0.89 for the 4 factors), and convergent validity was established, especially for the insomnia and irritability factors, alongside the total score with depressive symptoms, insomnia, quality of life, suicide risk, and physical health measures.

conclusionsThese results demonstrate the factor structure, reliability, and validity of the CAST-SR in a novel population of only individuals with stimulant use disorders receiving both exercise/health education interventions and antidepressant medication.

trial registrationClinicalTrials.gov identifier: NCT01141608.

Indexed as

Quality of LifeResidential TreatmentSubstance-Related DisordersCentral Nervous System StimulantsDiagnostic and Statistical Manual of Mental DisordersExerciseFemaleHealth EducationHumansIrritable MoodMalePsychiatric Status Rating ScalesPsychometricsReproducibility of ResultsSelf ReportSleep Initiation and Maintenance DisordersCentral Nervous System Stimulants

Identifiers

PMID29325238
PMCPMC5932219
OpenAlexW2781997452

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.