ArticleAnnals of botany2018
Hydrogen peroxide acts downstream of melatonin to induce lateral root formation.
Article in Annals of botany, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 123 citations in OpenAlex.
- Hydrogen Peroxide: Its Role in Plant Biology and Crosstalk with Signalling Networks.International journal of molecular sciences · 2018Pooled it
- Integrated physiological and transcriptomic analyses reveal MT-mediated aluminum tolerance mechanisms in celery.BMC plant biology · 2026Article
- Phytomelatonin in Ornamental Horticulture: A Comprehensive Review of Growth Promotion, Stress Tolerance, and Post-Harvest Quality.International journal of molecular sciences · 2026Review
- Melatonin: a multifaceted regulator of root development, stress responses, and hormonal crosstalk in horticultural crops.Frontiers in plant science · 2026Review
- SerotoninInternational journal of molecular sciences · 2025Article
- Synergistic effects of exogenous IAA and melatonin on seed priming and physiological biochemistry of three desert plants in saline-alkali soil.Plant signaling & behavior · 2024Article
- Hydrogen peroxide mediates melatonin-induced chilling tolerance in cucumber seedlings.Plant cell reports · 2024Article
- Hydrogen peroxide modulates the expression of the target of rapamycin (TOR) and cell division in Arabidopsis thaliana.Protoplasma · 2024Article
- Exogenous Melatonin Reinforces Photosynthesis, Antioxidant Defense and Gene Expression to Ameliorate NaPlants (Basel, Switzerland) · 2024Article
- Unveiling the secrets of abiotic stress tolerance in plants through molecular and hormonal insights.3 Biotech · 2024Review
- Exogenous melatonin alleviates sodium chloride stress and increases vegetative growth in Lonicera japonica seedlings via gene regulation.BMC plant biology · 2024Article
- Melatonin-Nitric Oxide Crosstalk in Plants and the Prospects of NOMela as a Nitric Oxide Donor.International journal of molecular sciences · 2024Review
- Elucidating the role of exogenous melatonin in mitigating alkaline stress in soybeans across different growth stages: a transcriptomic and metabolomic approach.BMC plant biology · 2024Article
- Melatonin Alleviates Antimony Toxicity by Regulating the Antioxidant Response and Reducing Antimony Accumulation inAntioxidants (Basel, Switzerland) · 2023Article
- IBA and melatonin increase trigonelline and caffeine during the induction and initiation of adventitious roots in Coffea arabica L. cuttings.Scientific reports · 2023Article
- Regulation of V-ATPase by Jasmonic Acid: Possible Role of Persulfidation.International journal of molecular sciences · 2023Article
- Why did glutamate, GABA, and melatonin become intercellular signalling molecules in plants?eLife · 2023Review
- Exogenous Melatonin Spray Enhances Salinity Tolerance inLife (Basel, Switzerland) · 2023Review
- Crosstalk between melatonin and reactive oxygen species in fruits and vegetables post-harvest preservation: An update.Frontiers in nutrition · 2023Review
- Crosstalk between Melatonin and Reactive Oxygen Species in Plant Abiotic Stress Responses: An Update.International journal of molecular sciences · 2022Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Although several studies have confirmed the beneficial roles of exogenous melatonin in lateral root (LR) formation, the molecular mechanism is still elusive. Here, the role of hydrogen peroxide (H2O2) in the induction of LR formation triggered by melatonin was investigated. Methods: Alfalfa (Medicago sativa 'Biaogan') and transgenic Arabidopsis seedlings were treated with or without melatonin, diphenyleneiodonium (DPI, NADPH oxidase inhibitor), N,N'-dimethylthiourea (DMTU, H2O2 scavenger), alone or combined. Then, H2O2 content was determined with 2',7'-dichlorofluorescein diacetate (H2DCFDA)-dependent fluorescence and spectrophotography. Transcript levels of cell cycle regulatory genes were analysed by real-time reverse transcription-PCR. Key Results: Application of exogenous melatonin not only increased endogenous H2O2 content but also induced LR formation in alfalfa seedlings. Consistently, melatonin-induced LR primordia exhibited an accelerated response. These inducible responses were significantly blocked when DPI or DMTU was applied. Compared with the wild-type, transgenic Arabidopsis plants overexpressing alfalfa MsSNAT (a melatonin synthesis gene) increased H2O2 accumulation and thereafter LR formation, both of which were blocked by DPI or DMTU. Similarly, melatonin-modulated expression of marker genes responsible for LR formation, including MsCDKB1;1, MsCDKB2;1, AtCDKB1;1 and AtCDKB2;1, was obviously impaired by the removal of H2O2 in both alfalfa and transgenic Arabidopsis plants. Conclusions: Pharmacological and genetic evidence revealed that endogenous melatonin-triggered LR formation was H2O2-dependent.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.