ArticlePloS one2018
Comparative transcriptome analysis reveals key genes potentially related to soluble sugar and organic acid accumulation in watermelon.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 63 citations in OpenAlex.
- Trial
- Comparative Transcriptomic Analysis Reveals Sugar Metabolism and Accumulation Mechanisms inLife (Basel, Switzerland) · 2026Article
- Transcriptome and Metabolomics Analysis of Sugar and Acid Metabolism Regulated by Different Storage Temperatures in Prunus domestica × armeniaca Fruits.Journal of food science · 2026Article
- Changes in Short- and Medium-Chain Fatty Acids and Sugars During Kombucha Fermentation of Tea and Coffee Byproducts and Their Relation to Sourness.Foods (Basel, Switzerland) · 2026Article
- Molecular orchestration of malate and citrate metabolism: regulatory networks governing organic acid dynamics and fruit quality attributes.Horticulture research · 2026Article
- Evolutionary and functional analysis of ARF and Aux/IAA gene families reveals their roles in sugar metabolism and watermelon domestication.Frontiers in plant science · 2026Article
- ClaPEPCK4: target gene for breeding innovative watermelon germplasm with low malic acid and high sweetness.GM crops & food · 2025Article
- Integrated Analysis of the Transcriptome and Metabolome Reveals the Network Regulating Fruit Taste in Sponge Gourd (Foods (Basel, Switzerland) · 2025Article
- Transcriptome reveals differential expression of flavor and color in closely related strains of tomato (PeerJ · 2025Article
- Watermelon fruit metabolome gene discovery and its application in breeding: a review.Frontiers in plant science · 2025Review
- Genome-Wide Identification and Expression Patterns of Cucumber Invertases and Their Inhibitor Genes.International journal of molecular sciences · 2023Article
- Comparative physiological and biochemical mechanisms in diploid, triploid, and tetraploid watermelon (Citrullus lanatus L.) grafted by branches.Scientific reports · 2023Article
- Combined Metabolome and Transcriptome Analysis Elucidates Sugar Accumulation in Wucai (International journal of molecular sciences · 2023Article
- Chemotaxonomic Identification of Key Taste and Nutritional Components in 'Shushanggan Apricot' Fruits by Widely Targeted Metabolomics.Molecules (Basel, Switzerland) · 2022Article
- Free Amino Acids and Volatile Aroma Compounds in Watermelon Rind, Flesh, and Three Rind-Flesh Juices.Molecules (Basel, Switzerland) · 2022Article
- Transcriptome Profiling to Dissect the Role of Genome Duplication on Graft Compatibility Mechanisms in Watermelon.Biology · 2022Article
- Genetic Analysis of Fruit Quality Traits in Sweet Watermelon (Frontiers in plant science · 2022Review
- Advances in Understanding and Harnessing the Molecular Regulatory Mechanisms of Vegetable Quality.Frontiers in plant science · 2022Review
- Identification of Key Gene Networks Controlling Soluble Sugar and Organic Acid Metabolism During Oriental Melon Fruit Development by Integrated Analysis of Metabolic and Transcriptomic Analyses.Frontiers in plant science · 2022Article
- A time-course transcriptome analysis of wax gourd fruit development reveals predominant genes regulating taste and nutrition.Frontiers in plant science · 2022Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Soluble sugars and organic acids are important components of fruit flavor and have a strong impact on the overall organoleptic quality of watermelon (Citrullus lanatus) fruit. Several studies have analyzed the expression levels of the genes related to soluble sugar accumulation and the dynamic changes in their content during watermelon fruit development and ripening. Nevertheless, to date, there have been no reports on the organic acid content in watermelon or the genes regulating their synthesis. In this study, the soluble sugars and organic acids in watermelon were measured and a comparative transcriptome analysis was performed to identify the key genes involved in the accumulation of these substances during fruit development and ripening. The watermelon cultivar '203Z' and its near-isogenic line (NIL) 'SW' (in the '203Z' background) were used as experimental materials. The results suggested that soluble sugar consist of fructose, glucose and sucrose while malic-, citric-, and oxalic acids are the primary organic acids in watermelon fruit. Several differentially expressed genes (DEGs) related to soluble sugar- and organic acid accumulation and metabolism were identified. These include the DEGs encoding raffinose synthase, sucrose synthase (SuSy), sucrose-phosphate synthase (SPSs), insoluble acid invertases (IAI), NAD-dependent malate dehydrogenase (NAD-cyt MDH), aluminum-activated malate transporter (ALMT), and citrate synthase (CS). This is the first report addressing comparative transcriptome analysis via NILs materials in watermelon fruit. These findings provide an important basis for understanding the molecular mechanism that leads to soluble sugar and organic acid accumulation and metabolism during watermelon fruit development and ripening.
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