ArticlePloS one2018
Early- and later-phases satellite cell responses and myonuclear content with resistance training in young men.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 52 citations in OpenAlex.
- Low-load blood flow-restricted resistance exercise produces fiber type-independent hypertrophy and improves muscle functional capacity in older individuals.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Trial
- Effects of Different Blood Flow Restriction Training Modes on Body Composition and Maximal Strength of Untrained Individuals.Life (Basel, Switzerland) · 2024Article
- Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions.Physiological reviews · 2023Review
- Is the myonuclear domain ceiling hypothesis dead?Singapore medical journal · 2023Review
- Influence of oestrogen on satellite cells and myonuclear domain size in skeletal muscles following resistance exercise.Journal of cachexia, sarcopenia and muscle · 2022Article
- A glitch in the matrix: the pivotal role for extracellular matrix remodeling during muscle hypertrophy.American journal of physiology. Cell physiology · 2022Review
- State of Knowledge on Molecular Adaptations to Exercise in Humans: Historical Perspectives and Future Directions.Comprehensive Physiology · 2022Article
- Sex-Based Differences in the Myogenic Response and Inflammatory Gene Expression Following Eccentric Contractions in Humans.Frontiers in physiology · 2022Article
- Fusion and beyond: Satellite cell contributions to loading-induced skeletal muscle adaptation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Review
- Myofibre Hypertrophy in the Absence of Changes to Satellite Cell Content Following Concurrent Exercise Training in Young Healthy Men.Frontiers in physiology · 2021Article
- Myogenic marker expression as a function of age and exercise-based therapy in the tongue.Experimental gerontology · 2020Article
- Effects of 12 Weeks of Resistance Training on Cardiovascular Risk Factors in School Adolescents.Medicina (Kaunas, Lithuania) · 2020Article
- Recent advances in understanding resistance exercise training-induced skeletal muscle hypertrophy in humans.F1000Research · 2020Review
- Eight weeks of resistance training increases strength, muscle cross-sectional area and motor unit size, but does not alter firing rates in the vastus lateralis.European journal of applied physiology · 2020Article
- Resistance training in young men induces muscle transcriptome-wide changes associated with muscle structure and metabolism refining the response to exercise-induced stress.European journal of applied physiology · 2018Article
- Satellite cell function, intramuscular inflammation and exercise in chronic kidney disease.Clinical kidney journal · 2018Article
- Review
- Prepubertal skeletal muscle growth requires Pax7-expressing satellite cell-derived myonuclear contribution.Development (Cambridge, England) · 2018Article
- The development of skeletal muscle hypertrophy through resistance training: the role of muscle damage and muscle protein synthesis.European journal of applied physiology · 2018Review
- Physiological Differences Between Low Versus High Skeletal Muscle Hypertrophic Responders to Resistance Exercise Training: Current Perspectives and Future Research Directions.Frontiers in physiology · 2018Review
Corrections and comments
- Erratum issued
Authors and funding
13 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Satellite cells (SC) are associated with skeletal muscle remodelling after muscle damage and/or extensive hypertrophy resulting from resistance training (RT). We recently reported that early increases in muscle protein synthesis (MPS) during RT appear to be directed toward muscle damage repair, but MPS contributes to hypertrophy with progressive muscle damage attenuation. However, modulations in acute-chronic SC content with RT during the initial (1st-wk: high damage), early (3rd-wk: attenuated damage), and later (10th-wk: no damage) stages is not well characterized. Ten young men (27 ± 1 y, 23.6 ± 1.0 kg·m-2) underwent 10-wks of RT and muscle biopsies (vastus-lateralis) were taken before (Pre) and post (48h) the 1st (T1), 5th (T2) and final (T3) RT sessions to evaluate fibre type specific SC content, cross-sectional area (fCSA) and myonuclear number by immunohistochemistry. We observed RT-induced hypertrophy after 10-wks of RT (fCSA increased ~16% in type II, P < 0.04; ~8% in type I [ns]). SC content increased 48h post-exercise at T1 (~69% in type I [P = 0.014]; ~42% in type II [ns]), and this increase was sustained throughout RT (pre T2: ~65%, ~92%; pre T3: ~30% [ns], ~87%, for the increase in type I and II, respectively, vs. pre T1 [P < 0.05]). Increased SC content was not coupled with changes in myonuclear number. SC have a more pronounced role in muscle repair during the initial phase of RT than muscle hypertrophy resulted from 10-wks RT in young men. Chronic elevated SC pool size with RT is important providing proper environment for future stresses or larger fCSA increases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.