ArticlePloS one2018
Slightly increased BMI at young age is a risk factor for future hypertension in Japanese men.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Association of weight status and the risks of diabetes in adults: a systematic review and meta-analysis of prospective cohort studies.International journal of obesity (2005) · 2022Pooled it
- A body mass index over 22 kg/m2 at college age is a risk factor for future diabetes in Japanese men.PloS one · 2019Trial
- Association of athlete's heart and ACE I/D genotype with later-life left ventricular hypertrophy: a retrospective cohort study.BMC cardiovascular disorders · 2026Article
- Socioeconomic disparities in multimorbidity of chronic diseases in the RaNCD cohort study.Scientific reports · 2025Article
- Engagement in different sport disciplines during university years and risk of locomotive syndrome in older age: J-FitEnvironmental health and preventive medicine · 2021Article
- Association of physical fitness and motor ability at young age with locomotive syndrome risk in middle-aged and older men: J-FitBMC geriatrics · 2021Article
- Distribution of risk factors of hypertension patients in different age groups in Tianjin.BMC public health · 2021Article
- Observational
- Body Mass Index Trajectories During Young Adulthood and Incident Hypertension: A Longitudinal Cohort in Chinese Population.Journal of the American Heart Association · 2019Article
- Advanced glycation end products and risk of hypertension in Iranian adults: Tehran lipid and glucose study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypertension is developed easily in Asian adults with normal body mass index (BMI) (~23 kg/m2), compared with other ethnicities with similar BMI. This study tested the hypothesis that slightly increased BMI at young age is a risk factor for future hypertension in Japanese men by historical cohort study.
methodsThe study participants were 636 male alumni of the physical education school. They had available data on their physical examination at college age and follow-up investigation between 2007 and 2011. The participants were categorized into six categories: BMI at college age of <20.0 kg/m2, 20.0-21.0kg/m2, 21.0-22.0kg/m2, 22.0-23.0kg/m2, 23.0-24.0kg/m2, and ≥24.0kg/m2, and the incidence of hypertension was compared.
resultsThis study covered 27-year follow-up period (interquartile range: IQR: 23-31) which included 17,059 person-years of observation. Subjects were 22 (22-22) years old at graduated college, and 49 (45-53) years old at first follow-up investigation. During the period, 120 men developed hypertension. The prevalence rates of hypertension for lowest to highest BMI categories were 9.4%, 14.6%, 16.1%, 17.5%, 30.3%, and 29.3%, respectively (p<0.001 for trend), and their hazard ratios were 1.00 (reference), 1.80 (95%CI: 0.65-4.94), 2.17 (0.83-5.64), 2.29 (0.89-5.92), 3.60 (1.37-9.47) and 4.72 (1.78-12.48), respectively (p<0.001 for trend). This trend was similar after adjustment for age, year of graduation, smoking, current exercise status and current dietary intake.
conclusionSlightly increased BMI at young age is a risk factor for future hypertension in Japanese men.
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