ArticleJournal of functional biomaterials2018
Quantitative Assessment of Antimicrobial Activity of PLGA Films Loaded with 4-Hexylresorcinol.
Article in Journal of functional biomaterials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Fabrication of PVA Coatings Applied to Electrospun PLGA Scaffolds to Prevent Postoperative Adhesions.Journal of functional biomaterials · 2025Article
- Fabrication of a Triple-Layer Bionic Vascular Scaffold via Hybrid Electrospinning.Journal of functional biomaterials · 2024Article
- Article
- The enhanced properties and bioactivity of poly-ε-caprolactone/poly lactic-RSC advances · 2023Article
- Biodegradable Water-Soluble Matrix for Immobilization of Biocidal 4-Hexylresorcinol.International journal of molecular sciences · 2023Article
- Antibacterial Activity and Cytocompatibility of Electrospun PLGA Scaffolds Surface-Modified by Pulsed DC Magnetron Co-Sputtering of Copper and Titanium.Pharmaceutics · 2023Article
- A Review of Commonly Used Methodologies for Assessing the Antibacterial Activity of Honey and Honey Products.Antibiotics (Basel, Switzerland) · 2022Review
- Effect of Polymeric Nanoparticles with Entrapped Fish Oil or Mupirocin on Skin Wound Healing Using a Porcine Model.International journal of molecular sciences · 2022Article
- Phosphonium-based ionic liquids as antifungal agents for conservation of heritage sandstone.RSC advances · 2022Article
- Protein and Polysaccharide-Based Electroactive and Conductive Materials for Biomedical Applications.Molecules (Basel, Switzerland) · 2021Review
- Potential ProbioticMicroorganisms · 2021Article
- Entrapment of Hydrophobic Biocides into Cellulose Acetate Nanoparticles by Nanoprecipitation.Nanomaterials (Basel, Switzerland) · 2020Article
- Antifungal Activity of Polyoxometalate-Ionic Liquids on Historical Brick.Molecules (Basel, Switzerland) · 2020Article
- Bactericidal activity of hexylresorcinol lozenges against oropharyngeal organisms associated with acute sore throat.BMC research notes · 2020Article
- The use of 4-Hexylresorcinol as antibiotic adjuvant.PloS one · 2020Article
- Formulation of Antimicrobial Tobramycin Loaded PLGA Nanoparticles via Complexation with AOT.Journal of functional biomaterials · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Profound screening and evaluation methods for biocide-releasing polymer films are crucial for predicting applicability and therapeutic outcome of these drug delivery systems. For this purpose, we developed an agar overlay assay embedding biopolymer composite films in a seeded microbial lawn. By combining this approach with model-dependent analysis for agar diffusion, antimicrobial potency of the entrapped drug can be calculated in terms of minimum inhibitory concentrations (MICs). Thus, the topical antiseptic 4-hexylresorcinol (4-HR) was incorporated into poly(lactic-co-glycolic acid) (PLGA) films at different loadings up to 3.7 mg/cm² surface area through a solvent casting technique. The antimicrobial activity of 4-HR released from these composite films was assessed against a panel of Gram-negative and Gram-positive bacteria, yeasts and filamentous fungi by the proposed assay. All the microbial strains tested were susceptible to PLGA-4-HR films with MIC values down to 0.4% (
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Registered trials
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