Evidence map›Paper›PMID 29324695›Full record

ArticleMolecules (Basel, Switzerland)2018

Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents.

Ayesha Zafar, Lisa I Pilkington, Natalie A Haverkate, Michelle van Rensburg, Euphemia Leung, Sisira Kumara, William A Denny, David Barker, Ali Alsuraifi, Clare Hoskins and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Disruption of Crystal Packing in Thieno[2,3-Molecules (Basel, Switzerland) · 2022
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ayesha ZafarSchool of Chemical Sciences, University of Auckland, 23 Symonds Street, 1142 Auckland, New Zealand. ash_imran@hotmail.com.
Lisa I PilkingtonSchool of Chemical Sciences, University of Auckland, 23 Symonds Street, 1142 Auckland, New Zealand. lisa.pilkington@auckland.ac.nz.
Natalie A HaverkateSchool of Chemical Sciences, University of Auckland, 23 Symonds Street, 1142 Auckland, New Zealand. nhav422@aucklanduni.ac.nz.
Michelle van RensburgSchool of Chemical Sciences, University of Auckland, 23 Symonds Street, 1142 Auckland, New Zealand.
Euphemia LeungAuckland Cancer Society Research Centre and Department of Molecular Medicine and Pathology, University of Auckland, 1142 Auckland, New Zealand. e.leung@auckland.ac.nz.
Sisira KumaraAuckland Cancer Society Research Centre and Department of Molecular Medicine and Pathology, University of Auckland, 1142 Auckland, New Zealand. s.kumara@auckland.ac.nz.
William A DennyAuckland Cancer Society Research Centre and Department of Molecular Medicine and Pathology, University of Auckland, 1142 Auckland, New Zealand. b.denny@auckland.ac.nz.
David BarkerSchool of Chemical Sciences, University of Auckland, 23 Symonds Street, 1142 Auckland, New Zealand. d.barker@auckland.ac.nz.
Ali AlsuraifiInstitute for Science and Technology in Medicine, Keele University, Stoke-on-Trent ST4 7QB, UK. a.t.y.alsuraifi@keele.ac.uk.
Clare HoskinsInstitute for Science and Technology in Medicine, Keele University, Stoke-on-Trent ST4 7QB, UK. c.hoskins@keele.ac.uk.ORCID 0000-0002-7200-0566
Jóhannes ReynissonSchool of Chemical Sciences, University of Auckland, 23 Symonds Street, 1142 Auckland, New Zealand. j.reynisson@auckland.ac.nz.ORCID 0000-0003-4174-9512

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is now established that the thieno[2,3-

Indexed as

Antineoplastic AgentsCell Line, TumorCell ProliferationHumansModels, MolecularMolecular ConformationMolecular StructurePolymersPyridinesSolubilityStructure-Activity RelationshipAntineoplastic AgentsPolymersPyridinesthieno(2,3-b)pyridine1H-pyrrolo[2,3-b]pyridinemolecular modellingmorpholine substitutionnano aggregatespolymer formulation

Identifiers

PMID29324695
PMCPMC6017400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.