ReviewInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society2018
Intrauterine Manipulator Use During Minimally Invasive Hysterectomy and Risk of Lymphovascular Space Invasion in Endometrial Cancer.
Review in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association of Myometrial Invasion With Lymphovascular Space Invasion, Lymph Node Metastasis, Recurrence, and Overall Survival in Endometrial Cancer: A Meta-Analysis of 79 Studies With 68,870 Patients.Frontiers in oncology · 2021Pooled it
- Uterine manipulator in total laparoscopic hysterectomy: safety and usefulness.Updates in surgery · 2020Pooled it
- Oncological Safety of Intrauterine Manipulator Use in Laparoscopic Hysterectomy for Endometrial Cancer: A Propensity Score-Matched Analysis.Medicina (Kaunas, Lithuania) · 2025Article
- Endometrial cancer recurrence after the use of a uterine manipulator during laparoscopic surgery.Gynecologic oncology reports · 2024Article
- Review
- Endometrial cancer: predictors and oncological safety of tumor tissue manipulation.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024Article
- A retrospective study of the effects of uterine manipulators on prognosis in patients with cervical cancer.The Journal of international medical research · 2024Article
- Minimally Invasive Surgery for Cervical Cancer in Light of the LACC Trial: What Have We Learned?Current oncology (Toronto, Ont.) · 2022Review
- Radical Hysterectomy for Cervical Cancer: the Right Surgical Approach.Current treatment options in oncology · 2022Review
- Role of uterine manipulator during laparoscopic endometrial cancer treatment.Translational cancer research · 2020Review
- Significance of abnormal peritoneal cytology on survival of women with stage I-II endometrioid endometrial cancer.Gynecologic oncology · 2018Observational
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveThis study aimed to examine an association between intrauterine manipulator (IUM) use and frequency of lymphovascular space invasion (LVSI) in women with endometrial cancer undergoing minimally invasive hysterectomy.
methodsA retrospective case-control study was conducted among stage I-IV endometrial cancer patients who underwent hysterectomy between 2008 and 2015. Medical records were reviewed for patient demographics, surgical details, and tumor characteristics. Women who underwent total laparoscopic hysterectomy (TLH) with IUM use were compared with women who underwent total abdominal hysterectomy (TAH). Review of archived medical record for data collection and propensity score matching were performed to adjust for background differences between TLH-IUM and TAH groups. A systematic literature review with pooled analysis was performed to examine frequency of LVSI.
resultsThere were 687 women who underwent hysterectomy for endometrial cancer. Of those, 419 women underwent TLH with IUM use and 194 women underwent TAH. The most common type of IUM was VCare (89.5%). There was no statistically significant difference in the frequency of LVSI between the 2 groups: 15.1% for TLH-IUM vs 19.9% for TAH (P = 0.14). After propensity score matching, frequencies of LVSI were similar between the 2 groups: 21.2% for TLH-IUM vs 19.6% for TAH (P = 0.78). Systematic literature review identified 1371 cases of TLH-IUM and 1246 cases of TAH performed for endometrial cancer, and frequencies of LVSI were similar between the 2 groups (15.0% vs 13.6%, P = 0.31).
conclusionOur study suggests that IUM use during TLH for endometrial cancer is not associated with increased frequency of LVSI.
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