ReviewGerontology2018
Developmental Origins of Health Span and Life Span: A Mini-Review.
Review in Gerontology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 50 citations in OpenAlex.
- Developmental origins of exceptional health and survival: a four-generation family cohort study.Nature communications · 2026Article
- Parental Alcohol Exposures Associate with Lasting Mitochondrial Dysfunction and Accelerated Aging in a Mouse Model.Aging and disease · 2024Article
- Umbilical cord blood thyroid hormones are inversely related to telomere length and mitochondrial DNA copy number.Scientific reports · 2024Article
- Prenatal exposures to phthalates and bisphenols in relation to oxidative stress: single pollutant and mixtures analyses.Environmental science and pollution research international · 2024Article
- The Metabolically Obese, Normal-Weight Phenotype in Young Rats Is Associated with Cognitive Impairment and Partially Preventable with Leptin Intake during Lactation.International journal of molecular sciences · 2023Article
- Exposure to PCB126 during the nursing period reversibly impacts early-life glucose tolerance.Frontiers in endocrinology · 2023Article
- Developmental programming-ageing effects in muscle strength of obese rat offspring in a sex-dependent manner.Journal of biosciences · 2023Article
- Why twin studies are important for health span science research: the case of maltreatment of aging adults.BMC geriatrics · 2022Review
- Integrating DNA Methylation Measures of Biological Aging into Social Determinants of Health Research.Current environmental health reports · 2022Review
- Perinatal Treatment with Leptin, but Not Celastrol, Protects from Metabolically Obese, Normal-Weight Phenotype in Rats.Nutrients · 2022Article
- Retinoic Acid: Sexually Dimorphic, Anti-Insulin and Concentration-Dependent Effects on Energy.Nutrients · 2022Review
- Perinatal Origins of Adult Disease and Opportunities for Health Promotion: A Narrative Review.Journal of personalized medicine · 2022Review
- Maternal depressive symptoms and stress during pregnancy as predictors of gestational age at birth and standardized body mass index from birth up to 2 years of age.BMC pregnancy and childbirth · 2021Article
- ω3PUFAs improve hepatic steatosis in postnatal overfed rats and HepG2 cells by inhibiting acetyl-CoA carboxylase.Food science & nutrition · 2021Article
- Activation of innate immunity during development induces unresolved dysbiotic inflammatory gut and shortens lifespan.Disease models & mechanisms · 2021Article
- Perspective on prenatal polychlorinated biphenyl exposure and the development of the progeny nervous system (Review).International journal of molecular medicine · 2021Review
- Cross-Sectional Estimation of Endogenous Biomarker Associations with Prenatal Phenols, Phthalates, Metals, and Polycyclic Aromatic Hydrocarbons in Single-Pollutant and Mixtures Analysis Approaches.Environmental health perspectives · 2021Article
- Obesity, Early Life Gut Microbiota, and Antibiotics.Microorganisms · 2021Review
- Prenatal famine exposure and adult health outcomes: an epigenetic link.Environmental epigenetics · 2021Review
- The Physiology of Reproduction -Frontiers in physiology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundA vast body of research has demonstrated that disease susceptibility and offspring health can be influenced by perinatal factors, which include both paternal and maternal behavior and environment. Offspring disease risk has the potential to affect the health span and life span of offspring. KEY
findingsVarious maternal factors, such as environmental toxicant exposure, diet, stress, exercise, age at conception, and longevity have the potential to influence age-associated diseases such as cardiovascular disease, obesity, diabetes, and cancer risk in offspring. Paternal factors such as diet, age at conception, and longevity can potentially impact offspring health span and life span-reducing traits as well. PRACTICAL IMPLICATIONS: Continued research could go a long way toward defining mechanisms of the developmental origins of life span and health span, and eventually establishing regimens to avoid negative developmental influences and to encourage positive interventions to potentially increase life span and improve health span in offspring.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.