ArticleAmerican journal of respiratory and critical care medicine2018
Association between Household Air Pollution Exposure and Chronic Obstructive Pulmonary Disease Outcomes in 13 Low- and Middle-Income Country Settings.
Article in American journal of respiratory and critical care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03984188 (Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD), which is not on this map. Cited by 106 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD
Who cites it
106 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Climate, Air Quality and Their Contribution to Cardiovascular Disease Morbidity and Mortality in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis.Global heart · 2025Pooled it
- Prevalence and incidence of chronic obstructive pulmonary disease in Latin America and the Caribbean: a systematic review and meta-analysis.BMC pulmonary medicine · 2022Pooled it
- Chronic obstructive pulmonary disease in sub-Saharan Africa.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022Pooled it
- Performance of alternative COPD case-finding tools: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2021Pooled it
- Nitrogen dioxide exposures from LPG stoves in a cleaner-cooking intervention trial.Environment international · 2021Trial
- Prevalence of abnormal spirometry and correlates of lung function decline among a population in rural Uganda.Journal of global health · 2026Article
- Hallmarks of lung cancer driven by inhalable particulate matter: From cell-intrinsic oncogenic traits to microenvironment remodeling.Innovation (Cambridge (Mass.)) · 2026Review
- Integrated spatial analysis and Gaussian dispersion modelling of airborne particulate matter from rice processing mill hubs in rural Bangladesh and associated public health risks.Environmental science and pollution research international · 2026Article
- Revealing inequities in chronic respiratory disease (CRD) care: An adapted Photovoice qualitative study in Malaysian primary care settings.NPJ primary care respiratory medicine · 2026Article
- Personal PM2.5 exposure and lung function among adults with and without HIV who have recovered from pneumonia in Kampala, Uganda.Annals of the American Thoracic Society · 2026Article
- Cooking With Liquefied Petroleum Gas or Biomass and Quality of Life: Results From a Randomized Controlled Trial.Indoor air · 2026Article
- Multi-level community dissemination of public health research: insights from the fuel to pot project case study in Kenya and Malawi.Frontiers in public health · 2026Article
- Exposure-response relationship between ambient PMFrontiers in public health · 2026Article
- Trends, cross-country inequalities and risk factors in the global burden of chronic obstructive pulmonary disease mortality, 1990-2021: a secondary data analysis of the Global Burden of Disease Study 2021.Tobacco induced diseases · 2026Article
- Sociodemographic Determinants of Hospitalized Exacerbations in Exposure-Defined COPD Phenotypes: A Nationwide Prospective Cohort Study in China.International journal of chronic obstructive pulmonary disease · 2026Article
- Exposure to Fine Particulate Air Pollution and Risk of Adverse Health Outcomes in Women and Children in Bangladesh.Current environmental health reports · 2025Review
- Reduced Serum sRAGE Levels Identify COPD and Reflect Disease Severity: Findings from a Cross-Sectional Study in India.Diagnostics (Basel, Switzerland) · 2025Article
- Body Mass Index and Bronchodilator Responsiveness in Adults: Analysis of 2 Population-Based Studies in 4 South American Countries.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2025Article
- Clinical Characteristics and Risk Factors for Severe Exacerbation in Never-Smokers with Chronic Obstructive Pulmonary Disease: A Retrospective Cohort Study.Healthcare (Basel, Switzerland) · 2025Article
- Article
46 more citing papers are in PubMed but not listed here.
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Authors and funding
15 authors.
Funding
Abstract
rationaleForty percent of households worldwide burn biomass fuels for energy, which may be the most important contributor to household air pollution.
objectivesTo examine the association between household air pollution exposure and chronic obstructive pulmonary disease (COPD) outcomes in 13 resource-poor settings.
methodsWe analyzed data from 12,396 adult participants living in 13 resource-poor, population-based settings. Household air pollution exposure was defined as using biomass materials as the primary fuel source in the home. We used multivariable regressions to assess the relationship between household air pollution exposure and COPD outcomes, evaluated for interactions, and conducted sensitivity analyses to test the robustness of our findings. MEASUREMENTS AND MAIN
resultsAverage age was 54.9 years (44.2-59.6 yr across settings), 48.5% were women (38.3-54.5%), prevalence of household air pollution exposure was 38% (0.5-99.6%), and 8.8% (1.7-15.5%) had COPD. Participants with household air pollution exposure were 41% more likely to have COPD (adjusted odds ratio, 1.41; 95% confidence interval, 1.18-1.68) than those without the exposure, and 13.5% (6.4-20.6%) of COPD prevalence may be caused by household air pollution exposure, compared with 12.4% caused by cigarette smoking. The association between household air pollution exposure and COPD was stronger in women (1.70; 1.24-2.32) than in men (1.21; 0.92-1.58).
conclusionsHousehold air pollution exposure was associated with a higher prevalence of COPD, particularly among women, and it is likely a leading population-attributable risk factor for COPD in resource-poor settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.