Evidence map›Paper›PMID 29323797›Full record

ArticleHuman brain mapping2018

Relations between cortical thickness, serotonin 1A receptor binding, and structural connectivity: A multimodal imaging study.

Rajapillai L I Pillai, Ashwin Malhotra, Deborah D Rupert, Bennett Weschler, John C Williams, Mengru Zhang, Jie Yang, J John Mann, Maria A Oquendo, Ramin V Parsey and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Pretreatment and early-treatment cortical thickness is associated with SSRI treatment response in major depressive disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018
    Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. European psychiatry : the journal of the Association of European Psychiatrists · 2023
    Article
  7. Article
  8. Molecular connectivity disruptions in males with major depressive disorder.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Article
  9. Review
  10. Adult neuroplasticity: A new “cure” for major depression?Journal of psychiatry & neuroscience : JPN · 2019
    Article
  11. Cognitive Control as a 5-HTFrontiers in psychology · 2019
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Rajapillai L I PillaiStony Brook University SOM, Stony Brook, New York.ORCID 0000-0003-4901-6663
Ashwin MalhotraDepartment of Neurology, New York-Presbyterian Weill Cornell Medical Center, New York, New York.
Deborah D RupertStony Brook University SOM, Stony Brook, New York.
Bennett WeschlerStony Brook University SOM, Stony Brook, New York.
John C WilliamsStony Brook University SOM, Stony Brook, New York.
Mengru ZhangDepartment of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York.
Jie YangDepartment of Family, Population, and Preventive Medicine, Stony Brook University, Stony Brook, New York.
J John MannDepartment of Biomedical Engineering, Columbia University, New York, New York.
Maria A OquendoDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philidelphia, Pennsylvania.
Ramin V ParseyDepartment of Psychiatry, Stony Brook University, Stony Brook, New York.
Christine DeLorenzoDepartment of Psychiatry, Stony Brook University, Stony Brook, New York.
Stony Brook University · USColumbia University · USCornell University · USUniversity of Pennsylvania · US

Funding

THE NEUROBIOLOGY OF SUICIDAL BEHAVIORP50MH062185 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MANN, JOSEPH JOHN · 2000 to 2009
$21.7M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM008444 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI FROHMAN, MICHAEL A. · 1992 to 2024
$12.6M
Neurobiology of Depression and AntidepressantsR01MH040695 · NIMH · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI MANN, JOSEPH JOHN · 1986 to 2014
$7.1M
Supplement to Lithium's Molecular Mechanism of Action and the Pathology of Bipolar DisordersR01MH090276 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI PARSEY, RAMIN V. · 2011 to 2015
$4.2M
Biological Predictors of Response to AntidepressantsR01MH074813 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PARSEY, RAMIN V. · 2006 to 2010
$2.3M
Characterization of a New Metabotropic Glutamate Receptor Subtype 5 PET LigandK01MH091354 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI DELORENZO, CHRISTINE · 2011 to 2014
$691k
In Vivo Neurochemistry and Electrophysiology of Bipolar Disorder and its TreatmentF30MH109412 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI PILLAI, RAJAPILLAI LABAN ISAAC · 2016 to 2019
$167k
NIGMS NIH HHS T32 GM008444NIMH NIH HHS F30 MH109412NIMH NIH HHS K01 MH091354NIMH NIH HHS P50 MH062185NIMH NIH HHS R01 MH040695NIMH NIH HHS R01 MH074813NIMH NIH HHS R01 MH090276
6 · The paper itself

Abstract

Serotonin 1A (5-HT

Indexed as

AdultBrainCarbon RadioisotopesDiffusion Tensor ImagingFemaleHumansMagnetic Resonance ImagingMajor Depressive DisorderMaleMultimodal ImagingNeural PathwaysOrgan SizePiperazinesPositron-Emission TomographyPyridinesRadiopharmaceuticalsCarbon RadioisotopesHTR1A protein, humanN-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamidePiperazinesPyridinesRadiopharmaceuticalsReceptor, Serotonin, 5-HT1A

Identifiers

PMID29323797
PMCPMC5769701
OpenAlexW2768877722

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.