Evidence map›Paper›PMID 29323674›Full record

ArticleChemical communications (Cambridge, England)2018

Can 5-methylcytosine analogues with extended alkyl side chains guide DNA methylation?

D Kotandeniya, C L Seiler, J Fernandez, S S Pujari, L Curwick, K Murphy, S Wickramaratne, S Yan, D Murphy, Yuk Y Sham and 1 more

Open access · greenAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 3 countries.

D KotandeniyaMasonic Cancer Center, 2231 6th St SE, Minneapolis, MN 55455, USA. trety001@umn.edu.
C L Seiler
J Fernandez
S S Pujari
L Curwick
K Murphy
S Wickramaratne
S Yan
D Murphy
Yuk Y Sham
N Y Tretyakova
Minneapolis Institute of Arts · USUniversity of Minnesota · US

Funding

Chemistry-Biology Interface Training GrantT32GM008700 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI DISTEFANO, MARK D · 1999 to 2018
$4.0M
Smoking-Induced Epigenetic Changes in the Lung: Role of DNA DemethylationR01CA095039 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI TRETYAKOVA, NATALIA Y · 2003 to 2022
$3.6M
NCI NIH HHS R01 CA095039NIGMS NIH HHS T32 GM008700
6 · The paper itself

Abstract

5-Methylcytosine (

Indexed as

DNA Methylation5-MethylcytosineCrystallography, X-RayDNADNA (Cytosine-5-)-Methyltransferase 1HumansModels, MolecularMolecular Structure5-MethylcytosineDNADNA (Cytosine-5-)-Methyltransferase 1DNMT1 protein, human

Identifiers

PMID29323674
PMCPMC5805131
OpenAlexW2782285531

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.