ArticleExperimental and clinical psychopharmacology2018
Effects of experimental pain induction on alcohol urge, intention to consume alcohol, and alcohol demand.
Article in Experimental and clinical psychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- A meta-analytic review of the effectiveness of mood inductions in eliciting emotion-based behavioral risk-taking and craving in the laboratory.Emotion (Washington, D.C.) · 2023Pooled it
- Pooled it
- Experimental manipulations of behavioral economic demand for addictive commodities: a meta-analysis.Addiction (Abingdon, England) · 2020Pooled it
- Acceptance versus distraction as coping strategies for acute pain and pain-induced alcohol urge and approach inclinations.Experimental and clinical psychopharmacology · 2025Trial
- Development of a Personalized Feedback Intervention Targeting Pain-Related Anxiety for Adults Reporting Hazardous Drinking and Chronic Pain: A Randomized Controlled Trial.Journal of studies on alcohol and drugs · 2024Trial
- Pain as a causal motivator of alcohol consumption: Associations with gender and race.Journal of psychopathology and clinical science · 2023Trial
- Analgesic effects of alcohol in adults with chronic jaw pain.Alcoholism, clinical and experimental research · 2022Trial
- Associations Between Pain and Substance Use Among Individuals Diagnosed with Ehlers-Danlos Syndromes or Generalized Hypermobility Spectrum Disorder.International journal of behavioral medicine · 2026Article
- Chronic Pain Acceptance Moderates the Association Between Pain Intensity and Alcohol Use Severity Among Veterans With Chronic Musculoskeletal Pain.Alcohol, clinical & experimental research · 2026Article
- Clinical pain intensity is associated with greater cannabis demand among people who regularly use cannabis.Pain reports · 2026Article
- Bidirectional relationships between pain and alcohol use among older adults: a scoping review.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Discrimination, depressive symptoms, and prescription opioid misuse among adults with chronic pain who engage in hazardous drinking.The American journal of drug and alcohol abuse · 2026Article
- A conceptual framework for the intersection of hyperalgesia and hyperkatifeia in alcohol addiction.Alcohol (Fayetteville, N.Y.) · 2025Review
- Adaptive Serum Biochemistry Responses to Ethanol Administration in a Mouse Model: Implications for Metabolic Regulation Under Analgesia.Molecules (Basel, Switzerland) · 2025Article
- Persistent inflammation does not promote aversion-resistant binge-like alcohol drinking in rats.Alcohol (Fayetteville, N.Y.) · 2025Article
- Associations of physical pain, alcohol use, and related factors in the daily lives of patients with chronic low back pain.Alcohol (Fayetteville, N.Y.) · 2025Article
- The association between pain and negative alcohol-related consequences among college students engaged in binge drinking: The moderating role of reward and relief drinking motives.Addictive behaviors · 2025Article
- Theoretical Frameworks and Mechanistic Aspects of Alcohol Addiction: Alcohol Addiction as a Reward Deficit/Stress Surfeit Disorder.Current topics in behavioral neurosciences · 2025Review
- Neural responses to stress and alcohol cues in individuals with pain with and without alcohol use disorder.Addiction biology · 2024Article
- Use and co-use of alcohol and cannabis following physical pain in the daily life of community adults engaged in regular substance use.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Research suggests one determinant of alcohol consumption may be physical pain, but there is no empirical evidence that pain has a causal effect on drinking. Therefore, the primary aim of this study was to test experimental pain as a determinant of several alcohol consumption proxies: self-reported urge to drink, intention to consume alcohol, and alcohol demand. This study also was designed to test negative affect as a mediator of the effects of pain on alcohol use proxies. We hypothesized that participants randomized to experimental pain induction (vs. no pain) would report greater urge, intention, and alcohol demand, and that these effects would be mediated by increased negative affect. Participants were healthy undergraduates who were moderate-heavy drinkers (N = 61). Experimental pain was induced using a novel capsaicin-heat model intended to approximate key features of clinical pain. Results indicated that participants in the pain condition subsequently endorsed greater urge and intention to drink. Furthermore, these effects were mediated by pain-induced negative affect. We observed no effect of pain on alcohol demand. This is the first study to demonstrate a causal effect of acute pain on urge and intention to drink. Given the close association between alcohol consumption, urge and intention to drink, these findings suggest that pain may influence alcohol consumption, which can have implications for individuals with co-occurring pain and alcohol use disorder (AUD). Specifically, individuals with co-occurring pain and AUD may drink to alleviate pain-related negative affect. Therefore, improving pain-coping skills may enhance pain-management abilities, subsequently reducing coping-motivated drinking. (PsycINFO Database Record
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.