Evidence map›Paper›PMID 29323499›Full record

ArticleNano letters2018

Nanometer Resolution Elemental Mapping in Graphene-Based TEM Liquid Cells.

Daniel J Kelly, Mingwei Zhou, Nick Clark, Matthew J Hamer, Edward A Lewis, Alexander M Rakowski, Sarah J Haigh, Roman V Gorbachev

Abstract read
In one paragraph

Article in Nano letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Chemical science · 2025
    Review
  6. Liquid Phase Electron Microscopy of Bacterial Ultrastructure.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Article
  7. Article
  8. Article
  9. Nanopipette dynamic microscopy unveils nano coffee ring.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Article
  11. Graphene sandwich-based biological specimen preparation for cryo-EM analysis.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Recent advances iniScience · 2023
    Review
  13. Article
  14. Article
  15. Toward Exotic Layered Materials: 2D Cuprous Iodide.Advanced materials (Deerfield Beach, Fla.) · 2022
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel J KellySchool of Materials, ‡School of Physics and Astronomy, and §National Graphene Institute, University of Manchester , Oxford Road, Manchester, M13 9PL, United Kingdom.ORCID 0000-0003-1318-3515
Mingwei ZhouSchool of Materials, ‡School of Physics and Astronomy, and §National Graphene Institute, University of Manchester , Oxford Road, Manchester, M13 9PL, United Kingdom.
Nick ClarkSchool of Materials, ‡School of Physics and Astronomy, and §National Graphene Institute, University of Manchester , Oxford Road, Manchester, M13 9PL, United Kingdom.
Matthew J HamerSchool of Materials, ‡School of Physics and Astronomy, and §National Graphene Institute, University of Manchester , Oxford Road, Manchester, M13 9PL, United Kingdom.
Edward A LewisSchool of Materials, ‡School of Physics and Astronomy, and §National Graphene Institute, University of Manchester , Oxford Road, Manchester, M13 9PL, United Kingdom.
Alexander M RakowskiSchool of Materials, ‡School of Physics and Astronomy, and §National Graphene Institute, University of Manchester , Oxford Road, Manchester, M13 9PL, United Kingdom.
Sarah J HaighSchool of Materials, ‡School of Physics and Astronomy, and §National Graphene Institute, University of Manchester , Oxford Road, Manchester, M13 9PL, United Kingdom.ORCID 0000-0001-5509-6706
Roman V GorbachevSchool of Materials, ‡School of Physics and Astronomy, and §National Graphene Institute, University of Manchester , Oxford Road, Manchester, M13 9PL, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We demonstrate a new design of graphene liquid cell consisting of a thin lithographically patterned hexagonal boron nitride crystal encapsulated on both sides with graphene windows. The ultrathin window liquid cells produced have precisely controlled volumes and thicknesses and are robust to repeated vacuum cycling. This technology enables exciting new opportunities for liquid cell studies, providing a reliable platform for high resolution transmission electron microscope imaging and spectral mapping. The presence of water was confirmed using electron energy loss spectroscopy (EELS) via the detection of the oxygen K-edge and measuring the thickness of full and empty cells. We demonstrate the imaging capabilities of these liquid cells by tracking the dynamic motion and interactions of small metal nanoparticles with diameters of 0.5-5 nm. We further present an order of magnitude improvement in the analytical capabilities compared to previous liquid cell data with 1 nm spatial resolution elemental mapping achievable for liquid encapsulated bimetallic nanoparticles using energy dispersive X-ray spectroscopy (EDXS).

Indexed as

EDX spectrum imaginggraphene liquid cellsin situ TEMnanoparticlesvan der Waals heterostructures

Identifiers

PMID29323499
PMCPMC5821409

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.