ArticleJournal of the American Chemical Society2018
Total Synthesis of (+)-Pleuromutilin.
Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 104 citations in OpenAlex.
- Formal Total Synthesis of (±)-Isoalantolactone.Organic letters · 2026Article
- Bioinspired total synthesis of (+)-pleuromutilin.Nature communications · 2026Article
- From Natural Products to Small Molecules: Recent Advancements in Anti-MRSA Therapeutics.ACS medicinal chemistry letters · 2025Review
- Molecular Complexity-Inspired Synthetic Strategies toward the Calyciphylline A-TypeJournal of the American Chemical Society · 2024Article
- Synthetic and Semisynthetic Compounds as Antibacterials Targeting Virulence Traits in Resistant Strains: A Narrative Updated Review.Antibiotics (Basel, Switzerland) · 2023Review
- Strategies to access the [5-8] bicyclic core encountered in the sesquiterpene, diterpene and sesterterpene series.Beilstein journal of organic chemistry · 2023Review
- Total synthesis of structurally diverse pleuromutilin antibiotics.Nature chemistry · 2022Article
- Diastereoselective Radical 1,4-Ester Migration: Radical Cyclizations of Acyclic Esters with SmIJournal of the American Chemical Society · 2022Article
- γ C-H Functionalization of Amines via Triple H-Atom Transfer of a Vinyl Sulfonyl Radical Chaperone.Journal of the American Chemical Society · 2022Article
- Unified, Asymmetric Total Synthesis of the Asnovolins and Related Spiromeroterpenoids: A Fragment Coupling Approach.Journal of the American Chemical Society · 2022Article
- Synthesis of Pleuromutilin.Journal of the American Chemical Society · 2022Article
- Samarium(ii) iodide-mediated reactions applied to natural product total synthesis.RSC advances · 2022Review
- Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance.eLife · 2022Article
- Evolution towards green radical generation in total synthesis.Chemical Society reviews · 2021Review
- Radical philicity and its role in selective organic transformations.Nature reviews. Chemistry · 2021Review
- Recent advances in the chemistry of ketyl radicals.Chemical Society reviews · 2021Article
- Synthesis of Complex Diterpenes: Strategies Guided by Oxidation Pattern Analysis.Accounts of chemical research · 2021Article
- SmIJournal of the American Chemical Society · 2021Article
- Re-engineering natural products to engage new biological targets.Natural product reports · 2020Article
- C-H functionalization reactions enabled by hydrogen atom transfer to carbon-centered radicals.Chemical science · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
An 18-step synthesis of the antibiotic (+)-pleuromutilin is disclosed. The key steps of the synthesis include a highly stereoselective SmI
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.