ArticleNature structural & molecular biology2018
RNA-DamID reveals cell-type-specific binding of roX RNAs at chromatin-entry sites.
Article in Nature structural & molecular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
20 citing papers in PubMed.
- A noncanonical role of roX RNAs in autosomal epigenetic repression.Nature communications · 2025Article
- TORC2 inhibition triggers yeast chromosome fragmentation through misregulated Base Excision Repair of clustered oxidation events.Nature communications · 2024Article
- Novel biological insights revealed from the investigation of multiscale genome architecture.Computational and structural biotechnology journal · 2023Review
- A micropeptide JunBP regulated by TGF-β promotes hepatocellular carcinoma metastasis.Oncogene · 2023Article
- Multiomic chromatin and transcription profiling with EpiDamID.Cell reports methods · 2022Article
- Profiling Protein-DNA Interactions Cell-Type-Specifically with Targeted DamID.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Article
- Distinct mechanisms mediate X chromosome dosage compensation inLife science alliance · 2021Article
- Non-coding RNAs in chromatin folding and nuclear organization.Cellular and molecular life sciences : CMLS · 2021Review
- Tissue-specific DamID protocol using nanopore sequencing.Journal of biological methods · 2021Article
- Architectural RNA in chromatin organization.Biochemical Society transactions · 2020Review
- Enhanced nucleotide chemistry and toehold nanotechnology reveals lncRNA spreading on chromatin.Nature structural & molecular biology · 2020Article
- Overcoming challenges and dogmas to understand the functions of pseudogenes.Nature reviews. Genetics · 2020Review
- Targeting of the Dosage-Compensated Male X-Chromosome during Early Drosophila Development.Cell reports · 2019Article
- Principles and Practices of Hybridization Capture Experiments to Study Long Noncoding RNAs That Act on Chromatin.Cold Spring Harbor perspectives in biology · 2019Review
- lncRedibly versatile: biochemical and biological functions of long noncoding RNAs.The Biochemical journal · 2019Review
- DamID as a versatile tool for understanding gene regulation.Development (Cambridge, England) · 2019Review
- Targeted DamID reveals differential binding of mammalian pluripotency factors.Development (Cambridge, England) · 2018Article
- Facultative dosage compensation of developmental genes on autosomes in Drosophila and mouse embryonic stem cells.Nature communications · 2018Article
- CATaDa reveals global remodelling of chromatin accessibility during stem cell differentiation in vivo.eLife · 2018Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Thousands of long noncoding RNAs (lncRNAs) have been identified in eukaryotic genomes, many of which are expressed in spatially and temporally restricted patterns. Nonetheless, the roles of the majority of these transcripts are still unknown. One of the mechanisms by which lncRNAs function is through the modulation of chromatin states. To assess the functions of lncRNAs, we developed RNA-DamID, a novel approach that detects lncRNA-genome interactions in a cell-type-specific manner in vivo with high sensitivity and accuracy. Identifying the cell-type-specific genome occupancy of lncRNAs is vital to understanding their mechanisms of action in development and disease. We used RNA-DamID to investigate targeting of the lncRNAs in the Drosophila dosage-compensation complex (DCC) and show that initial targeting is cell-type specific.
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Registered trials
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