ArticleScientific reports2018
Genome-wide association study reveals candidate genes influencing lipids and diterpenes contents in Coffea arabica L.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Pooled it
- Climate Change and Coffee Quality: Systematic Review on the Effects of Environmental and Management Variation on Secondary Metabolites and Sensory Attributes ofFrontiers in plant science · 2021Pooled it
- Mass Spectrometry-Based Lipidomics in Coffee: Linking Lipid Transformation to Flavor Formation and Quality Control.Foods (Basel, Switzerland) · 2026Review
- Genome association of carbohydrate metabolites provides new insights toward functional breeding in coffee.The plant genome · 2026Article
- Unlocking the Quality Potential of Liberoid Coffee: Advances in Composition, Processing, and Microbial Fermentation.Comprehensive reviews in food science and food safety · 2026Review
- FFrontiers in plant science · 2026Review
- Improving resilience of Arabica coffee plantations by cultivating F1 hybrid varieties: challenges to future seed production and enhancing farmers' access to modern varieties.Frontiers in plant science · 2026Review
- Identification of SNP Markers and Candidate Genes Associated with Major Agronomic Traits inPlants (Basel, Switzerland) · 2024Article
- Genomic-assisted breeding for climate-smart coffee.The plant genome · 2024Article
- Population size in QTL detection using quantile regression in genome-wide association studies.Scientific reports · 2023Article
- Hello darkness, my old friend: 3-KETOACYL-COENZYME A SYNTHASE4 is a branch point in the regulation of triacylglycerol synthesis in Arabidopsis thaliana.The Plant cell · 2023Article
- CRISPR technology towards genome editing of the perennial and semi-perennial crops citrus, coffee and sugarcane.Frontiers in plant science · 2023Review
- SNP markers identification by genome wide association study for chemical quality traits of coffee (Coffea spp.) Germplasm.Molecular biology reports · 2022Article
- Transcriptome and carotenoid profiling of different varieties ofPlant diversity · 2022Article
- A study using single-locus and multi-locus genome-wide association study to identify genes associated with teat number in Hu sheep.Animal genetics · 2022Article
- Genome-wide association study for resistance toFrontiers in plant science · 2022Article
- Identification of QTNs, QTN-by-environment interactions and genes for yield-related traits in rice using 3VmrMLM.Frontiers in plant science · 2022Article
- Multi-locus genome-wide association studies for five yield-related traits in rice.BMC plant biology · 2021Article
- Lipidomic and metabolomic profiles of Coffea canephora L. beans cultivated in Southwestern Nigeria.PloS one · 2021Article
- Resequencing 93 accessions of coffee unveils independent and parallel selection during Coffea species divergence.Plant molecular biology · 2020Article
Corrections and comments
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Authors and funding
18 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lipids, including the diterpenes cafestol and kahweol, are key compounds that contribute to the quality of coffee beverages. We determined total lipid content and cafestol and kahweol concentrations in green beans and genotyped 107 Coffea arabica accessions, including wild genotypes from the historical FAO collection from Ethiopia. A genome-wide association study was performed to identify genomic regions associated with lipid, cafestol and kahweol contents and cafestol/kahweol ratio. Using the diploid Coffea canephora genome as a reference, we identified 6,696 SNPs. Population structure analyses suggested the presence of two to three groups (K = 2 and K = 3) corresponding to the east and west sides of the Great Rift Valley and an additional group formed by wild accessions collected in western forests. We identified 5 SNPs associated with lipid content, 4 with cafestol, 3 with kahweol and 9 with cafestol/kahweol ratio. Most of these SNPs are located inside or near candidate genes related to metabolic pathways of these chemical compounds in coffee beans. In addition, three trait-associated SNPs showed evidence of directional selection among cultivated and wild coffee accessions. Our results also confirm a great allelic richness in wild accessions from Ethiopia, especially in accessions originating from forests in the west side of the Great Rift Valley.
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