Evidence map›Paper›PMID 29322557›Full record

ReviewYeast (Chichester, England)2018

Veni, vidi, vici: the success of wtf meiotic drivers in fission yeast.

José Fabricio López Hernández, Sarah E Zanders

Open access · hybridAbstract readReview
In one paragraph

Review in Yeast (Chichester, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. TheeLife · 2020
    Article
  5. Resistance to natural and synthetic gene drive systems.Journal of evolutionary biology · 2020
    Review
  6. Article
  7. Article
  8. Article
  9. Fertility Costs of Meiotic Drivers.Current biology : CB · 2019
    Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

José Fabricio López HernándezStowers Institute for Medical Research, Kansas City, MO, 64110, USA.
Sarah E ZandersStowers Institute for Medical Research, Kansas City, MO, 64110, USA.ORCID 0000-0003-1867-986X
Stowers Institute for Medical Research · US

Funding

Models of Selfishness: Molecular and Evolutionary Analyses of the Wtf Meiotic DriversDP2GM132936 · NIGMS · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI ZANDERS, SARAH ELIZABETH · 2018 to 2018
$2.5M
Mechanisms of meiotic drive and the functional consequences of rapid genome evolutionR00GM114436 · NIGMS · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI ZANDERS, SARAH ELIZABETH · 2016 to 2018
$747k
Mechanisms of meiotic drive and the functional consequences of rapid genome evolution in SchizosaccharomycesK99GM114436 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ZANDERS, SARAH ELIZABETH · 2015 to 2016
$112k
NIGMS NIH HHS DP2 GM132936NIGMS NIH HHS K99 GM114436NIGMS NIH HHS R00 GM114436
6 · The paper itself

Abstract

Meiotic drivers are selfish DNA loci that can bias their own transmission into gametes. Owing to their transmission advantages, meiotic drivers can spread in populations even if the drivers or linked variants decrease organismal fitness. Meiotic drive was first formally described in the 1950s and is thought to be a powerful force shaping eukaryotic genomes. Classic genetic analyses have detected the action of meiotic drivers in plants, filamentous fungi, insects and vertebrates. Several of these drive systems have limited experimental tractability and relatively little is known about the molecular mechanisms of meiotic drive. Recently, however, meiotic drivers were discovered in a yeast species. The Schizosaccharomyces pombe wtf gene family contains several active meiotic drive genes. This review summarizes what is known about the wtf family and highlights its potential as a highly tractable experimental model for molecular and evolutionary characterization of meiotic drive.

Indexed as

Genes, FungalGene RearrangementGenetic SpeciationMeiosisMicrobial ViabilityModels, GeneticPoisonsRepetitive Sequences, Nucleic AcidSchizosaccharomycesSpores, FungalPoisonsinfertilitymeiosismeitoic driveSchizosaccharomycesspeciation

Identifiers

PMID29322557
PMCPMC6033644
OpenAlexW2783177919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.