ArticleInternal and emergency medicine2018
Independent risk factors for mortality in critically ill patients with candidemia on Italian Internal Medicine Wards.
Article in Internal and emergency medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Shift in Candidemia Epidemiology and Emerging Fluconazole Resistance inJournal of fungi (Basel, Switzerland) · 2026Article
- A fluconazole population pharmacokinetics study to improve target attainment in critically ill patients.Infection · 2026Article
- The Impact of Epidemiological Trends and Guideline Adherence on Candidemia-Associated Mortality: A 14-Year Study in Northeastern Italy.Journal of fungi (Basel, Switzerland) · 2025Article
- Clinical and molecular features of candidemia: a three-year retrospective study in Northern Guizhou, China.Frontiers in cellular and infection microbiology · 2025Article
- Establishment and Validation of a Nomogram Clinical Prediction Model for Nosocomial Candidemia: An 18-Year Retrospective Analysis.Infection and drug resistance · 2024Article
- Mortality of Patients With Candidemia and COVID-19: A Systematic Review With Meta-analysis.Open forum infectious diseases · 2023Review
- The Diagnostic Relevance of β-D-Glucan for Candidemia within Internal Medicine Wards.Diagnostics (Basel, Switzerland) · 2022Article
- Candidemia in Internal Medicine: Facing the New Challenge.Mycopathologia · 2022Article
- Article
- HIV Infection as Risk Factor for Death among Hospitalized Persons with Candidemia, South Africa, 2012-2017.Emerging infectious diseases · 2021Article
- Article
- Epidemiological Characteristics and Drug Resistance of Fungemia in General Hospitals from 2010 to 2019.BioMed research international · 2021Article
- Clinical Characteristics and Outcomes of Candidemia Caused by Meyerozyma guilliermondii Complex in Cancer Patients Undergoing Surgery.Mycopathologia · 2020Article
- Epidemiology, clinical characteristics, and outcome of candidemia in critically ill patients in Germany: a single-center retrospective 10-year analysis.Annals of intensive care · 2020Article
- Factors associated with the development of septic shock in patients with candidemia: a post hoc analysis from two prospective cohorts.Critical care (London, England) · 2020Article
- Epidemiology, risk factors and outcomes ofEpidemiology and infection · 2019Article
- The Overlooked Immune State in Candidemia: A Risk Factor for Mortality.Journal of clinical medicine · 2019Article
- Epidemiology and prognostic factors of nosocomial candidemia in Northeast Brazil: A six-year retrospective study.PloS one · 2019Article
- Performance evaluation of the (1,3)-β-D-glucan detection assay in non-intensive care unit adult patients.Infection and drug resistance · 2019Article
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16 authors.
Funding
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Abstract
Candida is an increasing cause of bloodstream infection and is associated with significant morbidity and mortality. The aim of our study is to analyze risk factors for short-term mortality in patients with bloodstream Candida spp. infections admitted to Internal Medicine Wards (IMWs). This was a retrospective case-control study between January 2012 and December 2014 from four University Hospitals in Italy, where patients with candidemia dying within 30 days from diagnosis were matched to control cases with candidemia who survived in the same period of time. Two-hundred and fifty cases of candidemia were registered during the 36 months of enrollment. Among these, 112 patients died (45%) within 30 days from the first blood culture's positivity for Candida spp. At multivariate analysis, septic shock [odds ratio (95% CI) = 2.919 (1.62-5.35), p < 0.001] and concomitant chronic kidney failure [odds ratio (95% CI) = 2.296 (1.07-5.12), p = 0.036] were independent predictors of mortality. Low-dose chronic steroid therapy was protective [odds ratio (95% CI) = 0.461 (0.25-0.83), p = 0.011).
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