ArticleEuropean radiology2018
Whole-body ultra-low dose CT using spectral shaping for detection of osteolytic lesion in multiple myeloma.
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Dose optimization for CT scans of the temporal bone using spectral shaping tin filter.Journal of applied clinical medical physics · 2026Article
- Metal artifact reduction and contrast agent performance as a function of source spectral shape.Physics in medicine and biology · 2025Article
- Implementing tin-prefiltration in routine clinical CT scans of the lower extremity: impact on radiation dose.Skeletal radiology · 2025Article
- Effect of Spectral Filtering and Segmental X-ray Tube Current Switch-Off on Interventionalist's Scatter Exposure during CT Fluoroscopy.Bioengineering (Basel, Switzerland) · 2024Article
- Ultra-Low Dose CT Chest in Acute COVID-19 Pneumonia: A Pilot Study from India.Diagnostics (Basel, Switzerland) · 2023Article
- AI Denoising Improves Image Quality and Radiological Workflows in Pediatric Ultra-Low-Dose Thorax Computed Tomography Scans.Tomography (Ann Arbor, Mich.) · 2022Article
- Dose Reduction and Diagnostic Performance of Tin Filter-Based Spectral Shaping CT in Patients with Colorectal Cancer.Tomography (Ann Arbor, Mich.) · 2022Article
- Whole-body magnetic resonance imaging (WBMRI) versus whole-body computed tomography (WBCT) for myeloma imaging and staging.Skeletal radiology · 2022Review
- Comparison of Image Quality and Radiation Dose Between Single-Energy and Dual-Energy Images for the Brain With Stereotactic Frames on Dual-Energy Cerebral CT.Frontiers in radiology · 2022Article
- Ultra-low-dose CT versus radiographs for minor spine and pelvis trauma: a Bayesian analysis of accuracy.European radiology · 2021Article
- MRI versusEuropean radiology · 2020Article
- Organ dose and total effective dose of whole-body CT in multiple myeloma patients.Skeletal radiology · 2020Article
- Optimization of radiation dose for CT detection of lytic and sclerotic bone lesions: a phantom study.European radiology · 2020Article
- Prospective evaluation of ultra-low-dose contrast-enhanced 100-kV abdominal computed tomography with tin filter: effect on radiation dose reduction and image quality with a third-generation dual-source CT system.European radiology · 2019Article
- Cervical Spine CT Using Spectral Shaping: Can It Be a Solution to Overcome Artifacts in the Lower Cervical Spinal Region?Korean journal of radiology · 2019Article
- Whole Body Low Dose Computed Tomography Using Third-Generation Dual-Source Multidetector With Spectral Shaping: Protocol Optimization and Literature Review.Dose-response : a publication of International Hormesis SocietyArticle
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to investigate the radiation dose and image quality of a whole-body low-dose CT (WBLDCT) using spectral shaping at 100 kV (Sn 100 kV) for the assessment of osteolytic lesions in patients with multiple myeloma.
methodsThirty consecutive patients were retrospectively selected, who underwent a WBLDCT on a third-generation dual-source CT (DSCT) (Sn 100 kV, ref. mAs: 130). They were matched with patients, who were examined on a second-generation DSCT with a standard low-dose protocol (100 kV, ref. mAs: 111). Objective and subjective image quality, radiation exposure as well as the frequency of osteolytic lesions were evaluated.
resultsAll scans were of diagnostic image quality. Subjective overall image quality was significantly higher in the study group (p = 0.0003). Objective image analysis revealed that signal intensities, signal-to-noise ratio and contrast-to-noise ratio of the bony structures were equal or significantly higher in the control group. There was no significant difference in the frequency of osteolytic lesions (p = 0.259). The median effective dose of the study protocol was significantly lower (1.45 mSv vs. 5.65 mSv; p < 0.0001).
conclusionWBLDCT with Sn 100 kV can obtain sufficient image quality for the depiction of osteolytic lesions while reducing the radiation dose by approximately 74%. KEY POINTS: • Spectral shaping using tin filtration is beneficial for whole-body low-dose CT • Sn 100 kV yields sufficient image quality for depiction of osteolytic lesions • Whole-body low-dose CT can be performed with a median dose of 1.5 mSv.
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