Evidence map›Paper›PMID 29322315›Full record

Trial reportEuropean journal of nutrition2019

Effects of a casein hydrolysate versus intact casein on gastric emptying and amino acid responses.

Katy Horner, Elaine Drummond, Victoria O'Sullivan, Pedapati S C Sri Harsha, Lorraine Brennan

Abstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Katy HornerSchool of Agriculture and Food Science, Institute of Food and Health and Food for Health Ireland (FHI), University College Dublin, Belfield, Dublin 4, Ireland.
Elaine DrummondSchool of Agriculture and Food Science, Institute of Food and Health and Food for Health Ireland (FHI), University College Dublin, Belfield, Dublin 4, Ireland.
Victoria O'SullivanSchool of Agriculture and Food Science, Institute of Food and Health and Food for Health Ireland (FHI), University College Dublin, Belfield, Dublin 4, Ireland.
Pedapati S C Sri HarshaSchool of Agriculture and Food Science, Institute of Food and Health and Food for Health Ireland (FHI), University College Dublin, Belfield, Dublin 4, Ireland.
Lorraine BrennanSchool of Agriculture and Food Science, Institute of Food and Health and Food for Health Ireland (FHI), University College Dublin, Belfield, Dublin 4, Ireland. lorraine.brennan@ucd.ie.
University College Dublin · IEFood for Health Ireland · IE

Funding

Enterprise Ireland TC20130001
6 · The paper itself

Abstract

purposeMilk proteins and/or their hydrolysates have been reported to have beneficial effects for improving postprandial glycaemia. Gastric emptying is a major determinant of postprandial glycaemia, yet limited studies have examined the effects of intact milk proteins compared to hydrolysates on gastric emptying. We investigated gastric emptying of a casein hydrolysate compared to intact casein.

methodsNine overweight and obese adults (mean ± SD age: 59.5 ± 6.5 years and BMI 28.4 ± 2.6 kg/m

resultsLinear mixed model analysis showed no effect of treatment [F

conclusionsGastric emptying of a casein hydrolysate compared to intact casein does not differ. Mechanisms other than gastric emptying, for example the presence of a bioactive peptide sequence, may contribute to the glycaemic management effects of certain milk protein hydrolysates and warrant further investigation.

Indexed as

AcetaminophenAdultAgedAmino AcidsCaseinsCross-Over StudiesFemaleGastric EmptyingGlucoseHumansInsulinMaleMiddle AgedPostprandial PeriodAcetaminophenAmino Acidscasein hydrolysateCaseinsGlucoseInsulinCaseinGastric emptyingHydrolysatePostprandial glycaemia

Identifiers

PMID29322315
OpenAlexW2783788253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.