Evidence map›Paper›PMID 29322221›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2018

Feasibility of opportunistic osteoporosis screening in routine contrast-enhanced multi detector computed tomography (MDCT) using texture analysis.

M R K Mookiah, A Rohrmeier, M Dieckmeyer, K Mei, F K Kopp, P B Noel, J S Kirschke, T Baum, K Subburaj

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Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. CT image-based biomarkers for opportunistic screening of osteoporotic fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
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  7. Differentiation of benign and malignant vertebral fractures using a convolutional neural network to extract CT-based texture features.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
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  12. MR-based proton density fat fraction (PDFF) of the vertebral bone marrow differentiates between patients with and without osteoporotic vertebral fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
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  20. X-ray-based quantitative osteoporosis imaging at the spine.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

M R K MookiahPillar of Engineering Product Development, Singapore University of Technology and Design, Singapore, Singapore.
A RohrmeierDepartment of Radiology, Klinikum Landshut Achdorf, Landshut, Germany.
M DieckmeyerDepartment of Radiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
K MeiDepartment of Radiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
F K KoppDepartment of Radiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
P B NoelDepartment of Radiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
J S KirschkeDepartment of Neuroradiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
T BaumDepartment of Neuroradiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
K SubburajPillar of Engineering Product Development, Singapore University of Technology and Design, Singapore, Singapore. subburaj@sutd.edu.sg.ORCID http://orcid.org/0000-0003-0723-2405

Funding

Deutsche Forschungsgemeinschaft DFG BA 4906/2-1SRG EPD 2015 093
6 · The paper itself

Abstract

This study investigated the feasibility of opportunistic osteoporosis screening in routine contrast-enhanced MDCT exams using texture analysis. The results showed an acceptable reproducibility of texture features, and these features could discriminate healthy/osteoporotic fracture cohort with an accuracy of 83%.

introductionThis aim of this study is to investigate the feasibility of opportunistic osteoporosis screening in routine contrast-enhanced MDCT exams using texture analysis.

methodsWe performed texture analysis at the spine in routine MDCT exams and investigated the effect of intravenous contrast medium (IVCM) (n = 7), slice thickness (n = 7), the long-term reproducibility (n = 9), and the ability to differentiate healthy/osteoporotic fracture cohort (n = 9 age and gender matched pairs). Eight texture features were extracted using gray level co-occurrence matrix (GLCM). The independent sample t test was used to rank the features of healthy/fracture cohort and classification was performed using support vector machine (SVM).

resultsThe results revealed significant correlations between texture parameters derived from MDCT scans with and without IVCM (r up to 0.91) slice thickness of 1 mm versus 2 and 3 mm (r up to 0.96) and scan-rescan (r up to 0.59). The performance of the SVM classifier was evaluated using 10-fold cross-validation and revealed an average classification accuracy of 83%.

conclusionsOpportunistic osteoporosis screening at the spine using specific texture parameters (energy, entropy, and homogeneity) and SVM can be performed in routine contrast-enhanced MDCT exams.

Indexed as

AgedAged, 80 and overCancellous BoneContrast MediaFeasibility StudiesFemaleHumansIncidental FindingsMaleMass ScreeningMiddle AgedOsteoporosisOsteoporotic FracturesRadiographic Image Interpretation, Computer-AssistedReproducibility of ResultsRetrospective StudiesContrast MediaOpportunistic osteoporosis screeningSpineTexture analysisTrabecular bone microstructure

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.