Evidence map›Paper›PMID 29322011›Full record

ArticleJournal of traditional and complementary medicine2018

Safety evaluation of Bon-santé cleanser

O Awodele, O E Kale, A O Odewabi, M Ekor, B A Salau, A O Adefule-Ositelu

Open access · diamondAbstract read
In one paragraph

Article in Journal of traditional and complementary medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Prevention of seminal vesicle damage byPharmaceutical biology · 2023
    Article
  2. Protective effects of ThaiJournal of traditional and complementary medicine · 2022
    Article
  3. Journal of traditional and complementary medicine · 2020
    Article
  4. Research Progress of Male Reproductive Toxicity of Chinese Materia Medicas.Evidence-based complementary and alternative medicine : eCAM · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 2 countries.

O AwodeleDepartment of Pharmacology, Therapeutics, and Toxicology, College of Medicine, University of Lagos, Nigeria.
O E KaleDepartment of Pharmacology, Therapeutics, and Toxicology, College of Medicine, University of Lagos, Nigeria.
A O OdewabiDepartment of Chemical Pathology, Olabisi Onabanjo University Teaching Hospital, Nigeria.
M EkorDepartment of Pharmacology, School of Medical Sciences, University of Cape Coast, Ghana.
B A SalauDepartment of Chemical sciences, Redeemers University, Ede, Osun State, Nigeria.
A O Adefule-OsiteluGuinness Eye Center, Lagos University Teaching Hospital, Lagos State, Nigeria.
Babcock University · NGLagos University Teaching Hospital · NGOlabisi Onabanjo University · NGRedeemer's University · NGUniversity of Cape Coast · GHUniversity of Lagos · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe global increase in acceptance and use of herbal remedies in recent times is still accompanied with poor knowledge of their potential adverse effects and the toxicological implications of their use are underestimated.

methodsBon-santé Cleanser

resultsBSC (250 mg/kg) elevated (p < 0.05) follicle stimulating hormone and luteinizing hormone levels respectively. BSC decreased sperm motility and the live-dead ratio at 1000 mg/kg and reduced reproductive hormone at 500 mg/kg and 1000 mg/kg respectively. BSC at 500 mg/kg increased (p < 0.05,

conclusionOverall, our data suggest BSC at low doses may increase reproductive hormones regulated by FSH and LH as observed in this study. However, BSC administration should be done with caution as it may induce reproductive toxicity in large doses.

Indexed as

Biological elementsBon-santé Cleanser® capsuleHerbal capsuleMale reproductive functionToxicology

Identifiers

PMID29322011
PMCPMC5756022
OpenAlexW2647108579

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.