Evidence map›Paper›PMID 29321749›Full record

ArticleFrontiers in psychiatry2017

Gender and Age Effects on the Trajectory of Depression in Opioid Users during Methadone Maintenance Treatment.

Peng-Wei Wang, Huang-Chi Lin, Yi-Hsin Connie Yang, Chih-Yao Hsu, Kuan-Sheng Chung, Hung-Chi Wu, Cheng-Fang Yen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Peng-Wei WangDepartment of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Huang-Chi LinDepartment of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Yi-Hsin Connie YangDepartment of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chih-Yao HsuDepartment of Addiction Science, Kai-Suan Psychiatric Hospital, Kaohsiung, Taiwan.
Kuan-Sheng ChungDepartment of Addiction Science, Kai-Suan Psychiatric Hospital, Kaohsiung, Taiwan.
Hung-Chi WuDepartment of Community Science, Kai-Suan Psychiatric Hospital, Kaohsiung, Taiwan.
Cheng-Fang YenDepartment of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Kaohsiung Municipal Kai-Syuan Psychiatric Hospital · TWKaohsiung Medical University · TWKaohsiung Medical University Chung-Ho Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBoth heroin use and depression are significant health problems. Methadone maintenance treatment (MMT) can be of great benefit to heroin users. However, changes in the level of depression in heroin users during MMT are not clear. Gender and age are also important factors in the development of depression, and whether gender and age moderate changes in depression in heroin users during MMT warrants further study. This study aimed to explore: (1) the trajectory of depression in opioid users during MMT and (2) the moderating effects of gender and age on the trajectory of depression in opioid users receiving MMT.

methodA total of 294 intravenous heroin users were recruited into this 9-month observational study. The level of depression was measured at the intake interview and at follow-up interviews every 3 months. A latent growth model was used to analyze the trajectory of the level of depression among the participants.

resultsDepression improved rapidly during the first 3 months of MMT and slowly after the first 3 months in both the female and male heroin users. There was no gender difference in the level of depression at each follow-up point. The level of depression in the female heroin users decreased faster than that in the male heroin users. In addition, the level of depression in the younger heroin users decreased faster than that in the older subjects.

conclusionDepression in female and younger heroin users improved more rapidly than in male and older subjects, respectively.

Indexed as

addictionagedepressiongendermethadoneopioidtrajectory

Identifiers

PMID29321749
PMCPMC5733537
OpenAlexW2771579503

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.