Evidence map›Paper›PMID 29321730›Full record

ArticleFrontiers in systems neuroscience2017

Rhythmic Calcium Events in the Lamina Propria Network of the Urinary Bladder of Rat Pups.

Thomas J Heppner, Grant W Hennig, Mark T Nelson, Margaret A Vizzard

Open access · goldAbstract read
In one paragraph

Article in Frontiers in systems neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Thomas J HeppnerDepartment of Pharmacology, The Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, United States.
Grant W HennigDepartment of Pharmacology, The Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, United States.
Mark T NelsonDepartment of Pharmacology, The Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, United States.
Margaret A VizzardDepartment of Neurological Sciences, The Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, United States.
University of Vermont · US

Funding

Cystitis-Induced Plasticity of Micturition ReflexesR01DK051369 · NIDDK · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI VIZZARD, MARGARET ANN · 2003 to 2017
$5.4M
Developmental Plasticity of Micturition ReflexesR01DK060481 · NIDDK · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI VIZZARD, MARGARET ANN · 2002 to 2018
$4.5M
Center for Neuroscience ExcellenceP30GM103498 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI PARSONS, RODNEY L · 2012 to 2015
$4.3M
Ca2+ Sparks and Urinary Bladder Smooth Muscle ExcitabilityR37DK053832 · NIDDK · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI NELSON, MARK T · 2008 to 2017
$3.4M
CA++ SPARKS &URINARY BLADDER SMOOTH MUSCLE EXCITABILITYR01DK053832 · NIDDK · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI NELSON, MARK T · 1998 to 2006
$2.0M
CENTER FOR NEUROSCIENCE EXCELLENCEP30RR032135 · NCRR · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI PARSONS, RODNEY L · 2011 to 2011
$1.1M
Acquisition of a Yokogawa CSU-W1 Spinning Disk Confocal Microscopy SystemS10OD017969 · OD · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI PARSONS, RODNEY L · 2014 to 2014
$519k
Developmental plasticity of micturation reflexesR56DK060481 · NIDDK · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI VIZZARD, MARGARET ANN · 2008 to 2008
$232k
IRRITATION INDUCED PLASTICITY OF MICTURITION PATHWAYSR29DK051369 · NIDDK · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI VIZZARD, MARGARET ANN · 1996 to 2000
$109k
NCRR NIH HHS P30 RR032135NIDDK NIH HHS R01 DK051369NIDDK NIH HHS R01 DK053832NIDDK NIH HHS R01 DK060481NIDDK NIH HHS R29 DK051369NIDDK NIH HHS R37 DK053832NIDDK NIH HHS R56 DK060481NIGMS NIH HHS P30 GM103498NIH HHS S10 OD017969
6 · The paper itself

Abstract

The lamina propria contains a dense network of cells, including interstitial cells (ICs), that may play a role in bladder function by modulating communication between urothelium, nerve fibers and smooth muscle or acting as pacemakers. Transient receptor potential vanilloid 4 (TRPV4) channels allow cation influx and may be involved in sensing stretch or chemical irritation in urinary bladder. Urothelium was removed from rats (P0-Adult), cut into strips, and loaded with a Ca

Indexed as

ATPCPAnetworkPDGFRαpostnatal developmentTRPV4wavefront

Identifiers

PMID29321730
PMCPMC5732214
OpenAlexW2775427106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.