Evidence map›Paper›PMID 29321651›Full record

ArticleScientific reports2018

Auditory Neural Activity in Congenitally Deaf Mice Induced by Infrared Neural Stimulation.

Xiaodong Tan, Israt Jahan, Yingyue Xu, Stuart Stock, Changyow Claire Kwan, Carmen Soriano, Xianghui Xiao, Jaime García-Añoveros, Bernd Fritzsch, Claus-Peter Richter

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
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  4. Infrared light stimulates the cochlea through a mechanical displacement detected and amplified by hair cells.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  15. Article
  16. Article
  17. Optical stimulation of neural tissue.Healthcare technology letters · 2020
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Xiaodong TanDepartment of Otolaryngology, Northwestern University Feinberg School of Medicine, 320 E. Chicago Avenue, Searle 12-561, Chicago, IL, 60611, USA.ORCID http://orcid.org/0000-0003-0251-2774
Israt JahanDepartment of Biology, University of Iowa, 129 E. Jefferson Street, Iowa City, IA, 52242, USA.
Yingyue XuDepartment of Otolaryngology, Northwestern University Feinberg School of Medicine, 320 E. Chicago Avenue, Searle 12-561, Chicago, IL, 60611, USA.
Stuart StockDepartment of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, 303 E. Chicago Avenue, Chicago, IL, 60611, USA.
Changyow Claire KwanDepartment of Otolaryngology, Northwestern University Feinberg School of Medicine, 320 E. Chicago Avenue, Searle 12-561, Chicago, IL, 60611, USA.
Carmen SorianoAdvanced Photon Source, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL, 60439, USA.
Xianghui XiaoAdvanced Photon Source, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL, 60439, USA.
Jaime García-AñoverosDepartments of Anesthesiology, Physiology, and Neurology, Northwestern University Institute for Neuroscience, Ward 10-070, 303 East Chicago Avenue, Chicago, IL, 60611, USA.
Bernd FritzschDepartment of Biology, University of Iowa, 129 E. Jefferson Street, Iowa City, IA, 52242, USA.ORCID http://orcid.org/0000-0002-4882-8398
Claus-Peter RichterDepartment of Otolaryngology, Northwestern University Feinberg School of Medicine, 320 E. Chicago Avenue, Searle 12-561, Chicago, IL, 60611, USA. cri529@northwestern.edu.ORCID http://orcid.org/0000-0002-1423-4751
Northwestern University · USArgonne National Laboratory · USUniversity of Iowa · US

Funding

Understanding the Benefits of Infrared Nerve Stimulators for Neural InterfacesR01DC011855 · NIDCD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RICHTER, CLAUS-PETER · 2012 to 2016
$2.4M
Scrutinize bHLH transcription factors mediated organ of Corti cell fate determinaR03DC013655 · NIDCD · UNIVERSITY OF IOWA · PI JAHAN, ISRAT · 2013 to 2015
$453k
NIDCD NIH HHS R01 DC011855NIDCD NIH HHS R03 DC013655
6 · The paper itself

Abstract

To determine whether responses during infrared neural stimulation (INS) result from the direct interaction with spiral ganglion neurons (SGNs), we tested three genetically modified deaf mouse models: Atoh1-cre; Atoh1

Indexed as

Acoustic StimulationAmino Acid Transport Systems, AcidicAnimalsBasic Helix-Loop-Helix ProteinsDeafnessDeep Brain StimulationDisease Models, AnimalEvoked Potentials, Auditory, Brain StemGene Knockout TechniquesHair Cells, AuditoryInfrared RaysMaleMiceSpiral GanglionX-Ray MicrotomographyAmino Acid Transport Systems, AcidicAtoh1 protein, mouseBasic Helix-Loop-Helix ProteinsSlc17a8 protein, mouse

Identifiers

PMID29321651
PMCPMC5762820
OpenAlexW2782384463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.