ArticleScientific reports2018
Estimating the capacity for production of formamide by radioactive minerals on the prebiotic Earth.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Article
- Direct Synthesis of Formamide from COJournal of the American Chemical Society · 2023Article
- Setting the geological scene for the origin of life and continuing open questions about its emergence.Frontiers in astronomy and space sciences · 2023Article
- A Physicochemical Consideration of Prebiotic Microenvironments for Self-Assembly and Prebiotic Chemistry.Life (Basel, Switzerland) · 2022Review
- Origin of Species before Origin of Life: The Role of Speciation in Chemical Evolution.Life (Basel, Switzerland) · 2021Review
- Radiolysis generates a complex organosynthetic chemical network.Scientific reports · 2021Article
- Prebiotic Organic Chemistry of Formamide and the Origin of Life in Planetary Conditions: What We Know and What Is the Future.International journal of molecular sciences · 2021Review
- Prebiotic Reaction Networks in Water.Life (Basel, Switzerland) · 2020Review
- A continuous reaction network that produces RNA precursors.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- The Prebiotic Provenance of Semi-Aqueous Solvents.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2020Article
- Membraneless polyester microdroplets as primordial compartments at the origins of life.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Prebiotic Syntheses Under Shock in the Water - Formamide - Potassium Bicarbonate - Sodium Hydroxide System.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2019Article
- Chemomimesis and Molecular Darwinism in Action: From Abiotic Generation of Nucleobases to Nucleosides and RNA.Life (Basel, Switzerland) · 2018Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Water creates special problems for prebiotic chemistry, as it is thermodynamically favorable for amide and phosphodiester bonds to hydrolyze. The availability of alternative solvents with more favorable properties for the formation of prebiotic molecules on the early Earth may have helped bypass this so-called "water paradox". Formamide (FA) is one such solvent, and can serve as a nucleobase precursor, but it is difficult to envision how FA could have been generated in large quantities or accumulated in terrestrial surface environments. We report here the conversion of aqueous acetonitrile (ACN) via hydrogen cyanide (HCN) as an intermediate into FA by γ-irradiation under conditions mimicking exposure to radioactive minerals. We estimate that a radioactive placer deposit could produce 0.1‒0.8 mol FA km
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