ArticleScientific reports2018
Phenotypic responses to interspecies competition and commensalism in a naturally-derived microbial co-culture.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Quantifying synthetic bacterial community composition with flow cytometry: efficacy in mock communities and challenges in co-cultures.mSystems · 2025Article
- Strategies and tools to construct stable and efficient artificial coculture systems as biosynthetic platforms for biomass conversion.Biotechnology for biofuels and bioproducts · 2024Review
- Co-existence of two antibiotic-producing marine bacteria:Applied and environmental microbiology · 2024Article
- Vertical variations in microbial diversity, composition, and interactions in freshwater lake sediments on the Tibetan plateau.Frontiers in microbiology · 2023Article
- Facing Resistant Bacteria with Plant Essential Oils: Reviewing the Oregano Case.Antibiotics (Basel, Switzerland) · 2022Review
- Interspecies and Intrastrain Interplay amongMicroorganisms · 2022Review
- Article
- Cocultivation of Anaerobic Fungi with Rumen Bacteria Establishes an Antagonistic Relationship.mBio · 2021Article
- Leveraging Experimental Strategies to Capture Different Dimensions of Microbial Interactions.Frontiers in microbiology · 2021Review
- Metabolic modelling approaches for describing and engineering microbial communities.Computational and structural biotechnology journal · 2021Review
- Snowstorm Enhanced the Deterministic Processes of the Microbial Community in Cryoconite at Laohugou Glacier, Tibetan Plateau.Frontiers in microbiology · 2021Article
- Sustainable production of FAEE biodiesel using the oleaginous yeast Yarrowia lipolytica.MicrobiologyOpen · 2020Article
- Deep learning predicts microbial interactions from self-organized spatiotemporal patterns.Computational and structural biotechnology journal · 2020Article
- Ignoring social distancing: advances in understanding multi-species bacterial interactions.Faculty reviews · 2020Review
- Article
- Minimal Interspecies Interaction Adjustment (MIIA): Inference of Neighbor-Dependent Interactions in Microbial Communities.Frontiers in microbiology · 2019Article
- Do Organic Substrates Drive Microbial Community Interactions in Arctic Snow?Frontiers in microbiology · 2019Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The fundamental question of whether different microbial species will co-exist or compete in a given environment depends on context, composition and environmental constraints. Model microbial systems can yield some general principles related to this question. In this study we employed a naturally occurring co-culture composed of heterotrophic bacteria, Halomonas sp. HL-48 and Marinobacter sp. HL-58, to ask two fundamental scientific questions: 1) how do the phenotypes of two naturally co-existing species respond to partnership as compared to axenic growth? and 2) how do growth and molecular phenotypes of these species change with respect to competitive and commensal interactions? We hypothesized - and confirmed - that co-cultivation under glucose as the sole carbon source would result in competitive interactions. Similarly, when glucose was swapped with xylose, the interactions became commensal because Marinobacter HL-58 was supported by metabolites derived from Halomonas HL-48. Each species responded to partnership by changing both its growth and molecular phenotype as assayed via batch growth kinetics and global transcriptomics. These phenotypic responses depended on nutrient availability and so the environment ultimately controlled how they responded to each other. This simplified model community revealed that microbial interactions are context-specific and different environmental conditions dictate how interspecies partnerships will unfold.
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