Evidence map›Paper›PMID 29321413›Full record

ArticleInternal medicine (Tokyo, Japan)2018

Remission of Refractory Ascites and Discontinuation of Hemodialysis after Additional Rituximab to Long-term Glucocorticoid Therapy in a Patient with TAFRO Syndrome.

Hanako Tsurumi, Yoshihide Fujigaki, Tadashi Yamamoto, Risa Iino, Kei Taniguchi, Michito Nagura, Shigeyuki Arai, Yoshifuru Tamura, Tatsuru Ota, Shigeru Shibata and 4 more

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In one paragraph

Article in Internal medicine (Tokyo, Japan), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Hanako TsurumiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Yoshihide FujigakiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Tadashi YamamotoDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Risa IinoDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Kei TaniguchiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Michito NaguraDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Shigeyuki AraiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Yoshifuru TamuraDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Tatsuru OtaDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Shigeru ShibataDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Fukuo KondoDepartment of Pathology, Teikyo University Hospital, Japan.
Nozomu KuroseDepartment of Pathology and Laboratory Medicine, Kanazawa Medical University, Japan.
Yasufumi MasakiDepartment of Hematology and Immunology, Medicine, Kanazawa Medical University, Japan.
Shunya UchidaDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Teikyo University · JPKanazawa Medical University · JPTeikyo University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombocytopenia, ascites, myelofibrosis, renal dysfunction, and organomegaly (TAFRO) syndrome is a newly recognized but rare disease, and its treatment has not yet been established. We reported a 50-year-old woman with TAFRO syndrome diagnosed 2 years after the initial symptoms of a fever, fatigue, epigastric pain, edema, ascites, lymphadenopathy, thrombocytopenia and renal insufficiency. The patient showed refractory ascites and required hemodialysis under corticosteroid mono-therapy for suspected immune-mediated disease but was successfully treated with additive rituximab, resulting in improvement in her laboratory data, the withdrawal of hemodialysis and the disappearance of ascites. This case underscores the therapeutic utility of rituximab in patients with corticosteroid-resistant TAFRO syndrome, even long after the onset of the disease.

Indexed as

AscitesDrug Therapy, CombinationEdemaFemaleFeverGlucocorticoidsHumansImmunologic FactorsLymphadenopathyMiddle AgedPrimary MyelofibrosisRemission InductionRenal DialysisRenal InsufficiencyRituximabSyndromeGlucocorticoidsImmunologic FactorsRituximabascitescorticosteroidhemodialysisrituximabTAFRO syndromethrombocytopenia

Identifiers

PMID29321413
PMCPMC5995702
OpenAlexW2784046738

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.