Evidence map›Paper›PMID 29321407›Full record

ArticleInternal medicine (Tokyo, Japan)2018

Vertebral Osteomyelitis Caused by Helicobacter cinaedi Identified Using Broad-range Polymerase Chain Reaction with Sequencing of the Biopsied Specimen.

Ryota Hase, Takuya Hirooka, Takashi Itabashi, Yasunobu Endo, Yoshihito Otsuka

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Frontiers in microbiology · 2024
    Review
  2. IDCases · 2022
    Article
  3. Article
  4. A Case Of RecurrentJournal of bone and joint infection · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ryota HaseDepartment of Infectious Diseases, Japanese Red Cross Narita Hospital, Japan.
Takuya HirookaDepartment of Orthopedics, Japanese Red Cross Narita Hospital, Japan.
Takashi ItabashiDepartment of Orthopedics, Japanese Red Cross Narita Hospital, Japan.
Yasunobu EndoDepartment of Laboratory Medicine, Japanese Red Cross Narita Hospital, Japan.
Yoshihito OtsukaDepartment of Laboratory Medicine, Kameda Medical Center, Japan.
Japanese Red Cross Narita Hospital · JPKameda Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 65-year-old man presented with gradually exacerbating low back pain. Magnetic resonance imaging revealed vertebral osteomyelitis in the Th11-L2 vertebral bodies and discs. The patient showed negative findings on conventional cultures. Direct broad-range polymerase chain reaction (PCR) with sequencing of the biopsied specimen had the highest similarity to the 16S rRNA gene of Helicobacter cinaedi. This case suggests that direct broad-range PCR with sequencing should be considered when conventional cultures cannot identify the causative organism of vertebral osteomyelitis, and that this method may be particularly useful when the pathogen is a fastidious organism, such as H. cinaedi.

Indexed as

Polymerase Chain ReactionSequence Analysis, RNAAgedBiopsyHelicobacterHelicobacter InfectionsHumansLow Back PainMagnetic Resonance ImagingMaleOsteomyelitisRNA, Ribosomal, 16SThoracic VertebraeRNA, Ribosomal, 16Sbroad-range PCR with sequencingHelicobacter cinaedivertebral osteomyelitis

Identifiers

PMID29321407
PMCPMC5995724
OpenAlexW2782986393

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.