Evidence map›Paper›PMID 29321307›Full record

ArticleJournal of virology2018

Kaposi's Sarcoma-Associated Herpesvirus K8 Is an RNA Binding Protein That Regulates Viral DNA Replication in Coordination with a Noncoding RNA.

Dongcheng Liu, Yan Wang, Yan Yuan

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Dongcheng LiuInstitute of Human Virology and Ministry of Education Key Laboratory of Tropical Disease Control, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Yan WangInstitute of Human Virology and Ministry of Education Key Laboratory of Tropical Disease Control, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, China wang93@mail.sysu.edu.cn yuan2@pobox.upenn.edu.
Yan YuanInstitute of Human Virology and Ministry of Education Key Laboratory of Tropical Disease Control, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, China wang93@mail.sysu.edu.cn yuan2@pobox.upenn.edu.
Sun Yat-sen University · CNUniversity of Pennsylvania · US

Funding

Role of LANA-RBP-jk During Early KSHV InfectionP01CA174439 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ROBERTSON, ERLE S. · 2013 to 2018
$8.7M
NCI NIH HHS P01 CA174439
6 · The paper itself

Abstract

Kaposi's sarcoma-associated herpesvirus (KSHV) lytic replication and constant primary infection of fresh cells are crucial for viral tumorigenicity. The virus-encoded bZIP family protein K8 plays an important role in viral DNA replication in both viral reactivation and

Indexed as

DNA ReplicationGene Expression Regulation, ViralBasic-Leucine Zipper Transcription FactorsDNA, ViralHerpesvirus 8, HumanHumansRepressor ProteinsRNA-Binding ProteinsRNA, UntranslatedSarcoma, KaposiViral ProteinsBasic-Leucine Zipper Transcription FactorsDNA, ViralK8 protein, Human herpesvirus 8Repressor ProteinsRNA-Binding ProteinsRNA, UntranslatedViral Proteins7SK RNAhuman herpesvirus 8 (HHV-8)K8Kaposi's sarcoma-associated herpesvirus (KSHV)noncoding RNAori-LytPAN RNAT0.7 RNAT1.4 RNAviral lytic DNA replication

Identifiers

PMID29321307
PMCPMC5972905
OpenAlexW2782674931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.