Evidence map›Paper›PMID 29321237›Full record

SynthesisNeurology2018

Differences in risk factors for 3 types of stroke: UK prospective study and meta-analyses.

Alison J Price, F Lucy Wright, Jane Green, Angela Balkwill, Sau Wan Kan, TienYu Owen Yang, Sarah Floud, Mary E Kroll, Rachel Simpson, Cathie L M Sudlow and 2 more

Open access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Incidence of Stroke in People With Diabetes Compared to Those Without Diabetes: A Systematic Review.Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2023
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Observational
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Alison J PriceFrom the Nuffield Department of Population Health (A.J.P., F.L.W., J.G., A.B., S.W.K., T.Y.O.Y., S.F., R.S., V.B., G.K.R.) and National Perinatal Epidemiology Unit (M.E.K.), University of Oxford; London School of Hygiene and Tropical Medicine (A.J.P.); and Centre for Clinical Brain Science (C.L.M.S.), University of Edinburgh, UK. alison.price@lshtm.ac.uk.
F Lucy WrightFrom the Nuffield Department of Population Health (A.J.P., F.L.W., J.G., A.B., S.W.K., T.Y.O.Y., S.F., R.S., V.B., G.K.R.) and National Perinatal Epidemiology Unit (M.E.K.), University of Oxford; London School of Hygiene and Tropical Medicine (A.J.P.); and Centre for Clinical Brain Science (C.L.M.S.), University of Edinburgh, UK.
Jane GreenFrom the Nuffield Department of Population Health (A.J.P., F.L.W., J.G., A.B., S.W.K., T.Y.O.Y., S.F., R.S., V.B., G.K.R.) and National Perinatal Epidemiology Unit (M.E.K.), University of Oxford; London School of Hygiene and Tropical Medicine (A.J.P.); and Centre for Clinical Brain Science (C.L.M.S.), University of Edinburgh, UK.
Angela BalkwillFrom the Nuffield Department of Population Health (A.J.P., F.L.W., J.G., A.B., S.W.K., T.Y.O.Y., S.F., R.S., V.B., G.K.R.) and National Perinatal Epidemiology Unit (M.E.K.), University of Oxford; London School of Hygiene and Tropical Medicine (A.J.P.); and Centre for Clinical Brain Science (C.L.M.S.), University of Edinburgh, UK.
Sau Wan KanFrom the Nuffield Department of Population Health (A.J.P., F.L.W., J.G., A.B., S.W.K., T.Y.O.Y., S.F., R.S., V.B., G.K.R.) and National Perinatal Epidemiology Unit (M.E.K.), University of Oxford; London School of Hygiene and Tropical Medicine (A.J.P.); and Centre for Clinical Brain Science (C.L.M.S.), University of Edinburgh, UK.
TienYu Owen YangFrom the Nuffield Department of Population Health (A.J.P., F.L.W., J.G., A.B., S.W.K., T.Y.O.Y., S.F., R.S., V.B., G.K.R.) and National Perinatal Epidemiology Unit (M.E.K.), University of Oxford; London School of Hygiene and Tropical Medicine (A.J.P.); and Centre for Clinical Brain Science (C.L.M.S.), University of Edinburgh, UK.
Sarah FloudFrom the Nuffield Department of Population Health (A.J.P., F.L.W., J.G., A.B., S.W.K., T.Y.O.Y., S.F., R.S., V.B., G.K.R.) and National Perinatal Epidemiology Unit (M.E.K.), University of Oxford; London School of Hygiene and Tropical Medicine (A.J.P.); and Centre for Clinical Brain Science (C.L.M.S.), University of Edinburgh, UK.
Mary E KrollFrom the Nuffield Department of Population Health (A.J.P., F.L.W., J.G., A.B., S.W.K., T.Y.O.Y., S.F., R.S., V.B., G.K.R.) and National Perinatal Epidemiology Unit (M.E.K.), University of Oxford; London School of Hygiene and Tropical Medicine (A.J.P.); and Centre for Clinical Brain Science (C.L.M.S.), University of Edinburgh, UK.
Rachel SimpsonFrom the Nuffield Department of Population Health (A.J.P., F.L.W., J.G., A.B., S.W.K., T.Y.O.Y., S.F., R.S., V.B., G.K.R.) and National Perinatal Epidemiology Unit (M.E.K.), University of Oxford; London School of Hygiene and Tropical Medicine (A.J.P.); and Centre for Clinical Brain Science (C.L.M.S.), University of Edinburgh, UK.
Cathie L M SudlowFrom the Nuffield Department of Population Health (A.J.P., F.L.W., J.G., A.B., S.W.K., T.Y.O.Y., S.F., R.S., V.B., G.K.R.) and National Perinatal Epidemiology Unit (M.E.K.), University of Oxford; London School of Hygiene and Tropical Medicine (A.J.P.); and Centre for Clinical Brain Science (C.L.M.S.), University of Edinburgh, UK.
Valerie BeralFrom the Nuffield Department of Population Health (A.J.P., F.L.W., J.G., A.B., S.W.K., T.Y.O.Y., S.F., R.S., V.B., G.K.R.) and National Perinatal Epidemiology Unit (M.E.K.), University of Oxford; London School of Hygiene and Tropical Medicine (A.J.P.); and Centre for Clinical Brain Science (C.L.M.S.), University of Edinburgh, UK.
Gillian K ReevesFrom the Nuffield Department of Population Health (A.J.P., F.L.W., J.G., A.B., S.W.K., T.Y.O.Y., S.F., R.S., V.B., G.K.R.) and National Perinatal Epidemiology Unit (M.E.K.), University of Oxford; London School of Hygiene and Tropical Medicine (A.J.P.); and Centre for Clinical Brain Science (C.L.M.S.), University of Edinburgh, UK.
London School of Hygiene & Tropical Medicine · GB

Funding

Cancer Research UK 16491Cancer Research UK A16491Medical Research Council G0700474Medical Research Council MR/K02700X/1Wellcome Trust 103418
6 · The paper itself

Abstract

objectiveTo compare associations of behavioral and related factors for incident subarachnoid hemorrhage and intracerebral hemorrhage and ischemic stroke.

methodsA total of 712,433 Million Women Study participants without prior stroke, heart disease, or cancer reported behavioral and related factors at baseline (1999-2007) and were followed up by record linkage to national hospital admission and death databases. Cox regression yielded adjusted relative risks (RRs) by type of stroke. Heterogeneity was assessed with χ

resultsAfter 12.9 (SD 2.6) years of follow-up, 8,128 women had an incident ischemic stroke, 2,032 had intracerebral hemorrhage, and 1,536 had subarachnoid hemorrhage. In women with diabetes mellitus, the risk of ischemic stroke was substantially increased (RR 2.01, 95% confidence interval [CI] 1.84-2.20), risk of intracerebral hemorrhage was increased slightly (RR 1.31, 95% CI 1.04-1.65), but risk of subarachnoid hemorrhage was reduced (RR 0.43, 95% CI 0.26-0.69) (heterogeneity by stroke type,

conclusionClassic risk factors for stroke have considerably different effects on the 3 main pathologic types of stroke.

Indexed as

AgedBrain IschemiaDiabetes MellitusFemaleFollow-Up StudiesHumansIncidenceIntracranial HemorrhagesLife StyleMaleMiddle AgedObesityProspective StudiesRisk FactorsSmokingStroke

Identifiers

PMID29321237
PMCPMC5798656
OpenAlexW2782686757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.