ArticleJournal of orthopaedic surgery and research2018
Insufficient sensitivity of joint aspiration during the two-stage exchange of the hip with spacers.
Article in Journal of orthopaedic surgery and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Does Aspiration With Culture Augmented With Percutaneous Core Biopsy Analysis Have Better Diagnostic Value Than Culture Alone for PJI in Large Joints? A Prospective Enhancement and Feasibility Study.Clinical orthopaedics and related research · 2026Article
- Calcium hydroxide coating for orthopedic implants: evaluation of osseointegrative and antibacterial propertiesFrontiers in bioengineering and biotechnology · 2025Article
- Periprosthetic Joint Infections of the Knee-Comparison of Different Treatment Algorithms.Journal of clinical medicine · 2024Article
- Upcoming evidence in clinical practice of two-stage revision arthroplasty for prosthetic joint infection.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2024Review
- Rotational Thromboelastometry as a Diagnostic Tool for Persistent Infection in Two-Stage Exchange Arthroplasty.Journal of clinical medicine · 2024Article
- Interval between two-stage exchanges: what is optimal and how do you know?Arthroplasty (London, England) · 2023Review
- Role of joint aspiration before re-implantation in patients with a cement spacer in place.World journal of orthopedics · 2022Article
- The role of synovial fluid aspiration in shoulder joint infections.BMC musculoskeletal disorders · 2022Article
- Infection control and outcome of staged reverse shoulder arthroplasty for the management of shoulder infections.JSES international · 2020Article
- Twenty common errors in the diagnosis and treatment of periprosthetic joint infection.International orthopaedics · 2020Review
- Synovial Fluid Aspiration Should Not Be Routinely Performed during the Two-Stage Exchange of the Knee.BioMed research international · 2018Article
- Synovial Alpha-defensin at Reimplantation in Two-stage Revision Arthroplasty to Rule Out Persistent Infection.In vivo (Athens, Greece)Article
- Do not exchange the spacer during staged TKA exchange!Journal of orthopaedicsArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundEvaluation of infection persistence during the two-stage exchange of the hip is challenging. Joint aspiration before reconstruction is supposed to rule out infection persistence. Sensitivity and specificity of synovial fluid culture and synovial leucocyte count for detecting infection persistence during the two-stage exchange of the hip were evaluated.
methodsNinety-two aspirations before planned joint reconstruction during the two-stage exchange with spacers of the hip were retrospectively analyzed.
resultsThe sensitivity and specificity of synovial fluid culture was 4.6 and 94.3%. The sensitivity and specificity of synovial leucocyte count at a cut-off value of 2000 cells/μl was 25.0 and 96.9%. C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) values were significantly higher before prosthesis removal and reconstruction or spacer exchange (p = 0.00; p = 0.013 and p = 0.039; p = 0.002) in the infection persistence group. Receiver operating characteristic area under the curve values before prosthesis removal and reconstruction or spacer exchange for ESR were lower (0.516 and 0.635) than for CRP (0.720 and 0.671).
conclusionsSynovial fluid culture and leucocyte count cannot rule out infection persistence during the two-stage exchange of the hip.
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