Evidence map›Paper›PMID 29320902›Full record

ArticleLeukemia & lymphoma2018

CD33 splicing SNP regulates expression levels of CD33 in normal regenerating monocytes in AML patients.

Jatinder K Lamba, Andrew P Voigt, Lata Chauhan, Miyoung Shin, Richard Aplenc, Lisa Eidenschink Brodersen, Alan S Gamis, Soheil Meshinchi, Michael R Loken

Open access · greenAbstract readLetter
In one paragraph

Article in Leukemia & lymphoma, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. CAR-T cell therapy for cancer: current challenges and future directions.Signal transduction and targeted therapy · 2025
    Review
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jatinder K Lambaa Department of Pharmacotherapy and Translational Research , University of Florida , Gainesville , FL , USA.
Andrew P Voigtb Hematologics Inc , Seattle , WA , USA.
Lata Chauhana Department of Pharmacotherapy and Translational Research , University of Florida , Gainesville , FL , USA.
Miyoung Shina Department of Pharmacotherapy and Translational Research , University of Florida , Gainesville , FL , USA.
Richard Aplencc Children's Hospital of Philadelphia , Philadelphia , PA , USA.
Lisa Eidenschink Brodersenb Hematologics Inc , Seattle , WA , USA.
Alan S Gamisd Children's Mercy Hospitals and Clinics , Kansas City , MO , USA.
Soheil Meshinchie Fred Hutchinson Cancer Research Center , Seattle , WA , USA.
Michael R Lokenb Hematologics Inc , Seattle , WA , USA.
University of Florida · USChildren's Hospital of Philadelphia · USChildren's Mercy Hospital · USFred Hutch Cancer Center · US

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG FOREIGN ACCRUALU10CA098543 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI ADAMSON, PETER C. · 2003 to 2013
$335.5M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
Children's Oncology Group Statistics &Data Center GrantU10CA098413 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI DEVIDAS, MEENAKSHI · 2003 to 2013
$67.5M
Pharmacogenomics of Ara-C in AMLR01CA132946 · NCI · UNIVERSITY OF MINNESOTA · PI LAMBA, JATINDER K., POUNDS, STANLEY BARRETT · 2008 to 2025
$5.3M
Genetic Predictors of AML Treatment ResponseR01CA133881 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI APLENC, RICHARD · 2010 to 2014
$2.8M
Impact of genetic variation on response to GO therapy in COG-AML clinical trialsR21CA155524 · NCI · UNIVERSITY OF MINNESOTA · PI LAMBA, JATINDER K., WALTER, ROLAND BRUNO · 2012 to 2013
$439k
NCI NIH HHS R01 CA132946NCI NIH HHS R01 CA133881NCI NIH HHS R21 CA155524NCI NIH HHS U10 CA098413NCI NIH HHS U10 CA098543NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Polymorphism, Single NucleotideAcute DiseaseAllelesAlternative SplicingChildGene Expression RegulationGene FrequencyGenotypeHEK293 CellsHumansK562 CellsLeukemia, MyeloidMonocytesSialic Acid Binding Ig-like Lectin 3CD33 protein, humanSialic Acid Binding Ig-like Lectin 3

Identifiers

PMID29320902
PMCPMC7199442
OpenAlexW2783920336

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.