Evidence map›Paper›PMID 29320761›Full record

ArticleStem cell reports2018

Expandable Arterial Endothelial Precursors from Human CD34

Auston Z Miller, Alexander Satchie, Alex P Tannenbaum, Aman Nihal, James A Thomson, David T Vereide

Abstract read
In one paragraph

Article in Stem cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Auston Z MillerMorgridge Institute for Research, Madison, WI 53715, USA.
Alexander SatchieMorgridge Institute for Research, Madison, WI 53715, USA.
Alex P TannenbaumMorgridge Institute for Research, Madison, WI 53715, USA.
Aman NihalMorgridge Institute for Research, Madison, WI 53715, USA.
James A ThomsonMorgridge Institute for Research, Madison, WI 53715, USA; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106, USA.
David T VereideMorgridge Institute for Research, Madison, WI 53715, USA. Electronic address: dvereide@morgridge.org.

Funding

Transplantation of MHC Homozygous Vascular Progenitors in PrimatesU01HL134655 · NHLBI · MORGRIDGE INSTITUTE FOR RESEARCH, INC. · PI SLUKVIN, IGOR I. · 2016 to 2022
$7.7M
NHLBI NIH HHS U01 HL134655
6 · The paper itself

Abstract

Arterial diseases continue to pose a major health concern but in vitro studies are limited because explanted cells can exhibit poor proliferative capacity and a loss of specificity. Here, we find that two transcription factors, MYCN and SOX17, induce and indefinitely expand in culture precursors of human arterial endothelial cells (expandable arterial endothelial precursors [eAEPs]). The eAEPs are derived from CD34

Indexed as

Cell DifferentiationAntigens, CD34Bone Marrow CellsEndothelial Progenitor CellsFetal BloodHumansN-Myc Proto-Oncogene ProteinOrgan SpecificitySOXF Transcription FactorsAntigens, CD34MYCN protein, humanN-Myc Proto-Oncogene ProteinSOX17 protein, humanSOXF Transcription Factorsarterial endothelial precursorsendothelial-to-mesenchymal transitionMYCNreprogrammingself-renewalSOX17transcription factors

Identifiers

PMID29320761
PMCPMC5769011

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.