ArticleCell metabolism2018
SERCA2b Cycles Its Way to UCP1-Independent Thermogenesis in Beige Fat.
Article in Cell metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Weighing in on the role of brown adipose tissue for treatment of obesity.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2024Review
- A PPARγ/long noncoding RNA axis regulates adipose thermoneutral remodeling in mice.The Journal of clinical investigation · 2023Article
- A general overview of the multifactorial adaptation to cold: biochemical mechanisms and strategies.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Review
- An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin.Frontiers in endocrinology · 2023Review
- ATP-consuming futile cycles as energy dissipating mechanisms to counteract obesity.Reviews in endocrine & metabolic disorders · 2022Review
- The effects of neurogranin knockdown on SERCA pump efficiency in soleus muscles of female mice fed a high fat diet.Frontiers in endocrinology · 2022Article
- Endocrine role of bone in the regulation of energy metabolism.Bone research · 2021Review
- Disabling MNK protein kinases promotes oxidative metabolism and protects against diet-induced obesity.Molecular metabolism · 2020Article
- Neuronatin regulates whole-body metabolism: is thermogenesis involved?FASEB bioAdvances · 2020Article
- Thermogenic adipocytes: lineage, function and therapeutic potential.The Biochemical journal · 2020Review
- Sustained mitochondrial biogenesis is essential to maintain caloric restriction-induced beige adipocytes.Metabolism: clinical and experimental · 2020Article
- Urolithin A exerts antiobesity effects through enhancing adipose tissue thermogenesis in mice.PLoS biology · 2020Article
- Bone marrow adipose tissue does not express UCP1 during development or adrenergic-induced remodeling.Scientific reports · 2019Article
- Environmental and Nutritional Effects Regulating Adipose Tissue Function and Metabolism Across Generations.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019Review
Corrections and comments
- Comment on
Authors and funding
3 authors.
Funding
Abstract
A new study in Nature Medicine, by Ikeda et al. (2017), reports that calcium cycling in beige adipocytes elevates energy expenditure and glucose oxidation in the absence of uncoupling protein 1. Thermogenic calcium cycling in beige fat is mediated by SERCA2b and improves cold tolerance and metabolic status.
Indexed as
Identifiers
29320712What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.