Evidence map›Paper›PMID 29320705›Full record

ArticleCell metabolism2018

An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents.

Fang Zhang, Guiyang Hao, Mengle Shao, Kien Nham, Yu An, Qiong Wang, Yi Zhu, Christine M Kusminski, Gedaa Hassan, Rana K Gupta and 4 more

Abstract read
In one paragraph

Article in Cell metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
147citing papers in PubMed, 1 pooled it
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

147 citing papers in PubMed, 1 synthesis or guideline pooled it, 258 citations in OpenAlex.

  1. Guideline
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  11. PDGFRαAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  12. Harmonizing mouse anatomy terminology: a common language?Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Review
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87 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Fang ZhangTouchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Guiyang HaoDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-8542, USA.
Mengle ShaoTouchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Kien NhamDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-8542, USA.
Yu AnTouchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Qiong WangTouchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Yi ZhuTouchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Christine M KusminskiTouchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Gedaa HassanDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-8542, USA.
Rana K GuptaTouchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Qiwei ZhaiKey Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Xiankai SunDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-8542, USA.
Philipp E SchererTouchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: philipp.scherer@utsouthwestern.edu.
Orhan K OzDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-8542, USA. Electronic address: orhan.oz@utsouthwestern.edu.
The University of Texas Southwestern Medical Center · USChinese Academy of Sciences · CNSouthwestern Medical Center · US

Funding

Novel Mechanisms Regulating the Adipocyte-Brain-Hepatocyte AxisP01DK088761 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI HORTON, JAY D. · 2010 to 2019
$17.4M
Adiponectin, A Protein Secreted From Adipose TissueR01DK055758 · NIDDK · YESHIVA UNIVERSITY · PI SCHERER, PHILIPP E · 2000 to 2024
$10.9M
White Adipose Tissue Physiology, Mitochondrial Function and AdiponectinR01DK099110 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI PHILIPP E SCHERER · 2013 to 2026
$6.7M
Establishment and Maintenance of Healthy Adipose Tissue in ObesityR01DK104789 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI GUPTA, RANA K · 2015 to 2024
$3.9M
Noninvasive Assessment of Pancreatic Beta-Cell MassR01DK092163 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI OZ, ORHAN KEMAL, SUN, XIANKAI · 2011 to 2014
$1.5M
Dissecting Adipose Depot-Selective Regulation of Gene ProgramsRC1DK086629 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI SCHERER, PHILIPP E · 2009 to 2010
$1000k
The UTSW Small Animal SPECT-CT for Molecular Imaging Research and EducationS10RR029674 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI OZ, ORHAN KEMAL · 2010 to 2010
$894k
Gap Junction Dependent and Independent Roles of Connexin43 in Metabolic TissuesR00DK114498 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI ZHU, YI · 2020 to 2022
$733k
Converting More Brown Adipocytes From Resting to Active StateK01DK107788 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI WANG, QIONG ANNABEL · 2015 to 2017
$333k
Gap Junction Dependent and Independent Roles of Connexin43 in Metabolic TissuesK99DK114498 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI ZHU, YI · 2017 to 2018
$182k
NCRR NIH HHS S10 RR029674NIDDK NIH HHS K01 DK107788NIDDK NIH HHS K99 DK114498NIDDK NIH HHS P01 DK088761NIDDK NIH HHS R00 DK114498NIDDK NIH HHS R01 DK055758NIDDK NIH HHS R01 DK092163NIDDK NIH HHS R01 DK099110NIDDK NIH HHS R01 DK104789NIDDK NIH HHS RC1 DK086629
6 · The paper itself

Abstract

[

Indexed as

Imaging, Three-DimensionalAdipocytesAdipose Tissue, BeigeAdipose Tissue, BrownAdipose Tissue, WhiteAdolescentAnimalsBiomarkersFatty AcidsFluorodeoxyglucose F18Gene Expression RegulationHumansIodobenzenesLipodystrophyMaleMice, Inbred C57BLBiomarkersFatty AcidsFluorodeoxyglucose F18Iodobenzenesiodofiltic acidBATbeigebona fide thermogenic fat tissuesglucose or fatty acid imaging tracershuman-likeimagingmarker genesmorphologyPET/CTSPECT/CT

Identifiers

PMID29320705
PMCPMC5764189
OpenAlexW2783406277

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.