Trial reportPloS one2018
Undiagnosed abnormal postpartum blood loss: Incidence and risk factors.
Trial report in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Carbetocin Versus Oxytocin for Prophylaxis Against Atonic Primary Post-partum Hemorrhage in High-risk Patients in Sohag University Hospital: A Randomized Controlled Clinical Trial
Incidence and Risk Factors of Postpartum Hemorrhage at the Brugmann University Hospital in Comparison to the Literature
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Effects of Race, Ethnicity and Socioeconomic Deprivation on Postpartum Haemorrhage in High-Income Countries: A Systematic Review and Meta-Analysis.BJOG : an international journal of obstetrics and gynaecology · 2025Pooled it
- A cluster-randomized, non-inferiority trial comparing use of misoprostol for universal prophylaxis vs. secondary prevention of postpartum hemorrhage among community level births in Egypt.BMC pregnancy and childbirth · 2020Trial
- Trial
- Clinical predictors of postpartum vaginal and vulvar hematomas and the need for surgical treatment.Pregnancy (Hoboken, N.J.) · 2026Article
- Forensic expertise in evaluation of malpractice or complications in cases of early postpartum hemorrhage.Forensic science, medicine, and pathology · 2025Article
- Quantitative blood loss values reveal high rates of undiagnosed postpartum hemorrhage.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Article
- Evolution of Episiotomy Incidence and Obstetric Anal Sphincter Injury Over 10 Years: A Mixed-Methods Study.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Development and Validation of a Predictive Model for Postpartum Hemorrhage in Non-Primiparous Women Who Deliver Vaginally.Risk management and healthcare policy · 2025Article
- Prognostic Role of Initial Thromboelastography in Emergency Department Patients with Primary Postpartum Hemorrhage: Association with Massive Transfusion.Journal of personalized medicine · 2024Article
- Change in Hemoglobin Was Not a Reliable Diagnostic Screening Test for Postpartum Hemorrhage: A French Prospective Multicenter Cohort Study (HERA Study).Healthcare (Basel, Switzerland) · 2023Article
- Influence of the maternity unit and region of delivery on episiotomy practice in France: a nationwide population-based study.Acta obstetricia et gynecologica Scandinavica · 2023Article
- How to Improve the Care of Women after Childbirth in the Rooming-in Unit: A Prospective Observational Study.International journal of environmental research and public health · 2022Observational
- Midwives' ability during third stage of childbirth to estimate postpartum haemorrhage.European journal of obstetrics & gynecology and reproductive biology: X · 2022Article
- Episiotomy for Medical Indications during Vaginal Birth-Retrospective Analysis of Risk Factors Determining the Performance of This Procedure.Journal of clinical medicine · 2022Article
- Article
- Risk Factors for Carbetocin Failure after a Cesarean Section: Is Obesity One of Them?Journal of clinical medicine · 2021Article
- Observational
- Factors affecting third-stage management and postpartum hemorrhage in planned midwife-led home and birth center births in the United States.Birth (Berkeley, Calif.) · 2020Article
- Maternal death and postpartum hemorrhage in sub-Saharan Africa - A pilot study in metropolitan Mozambique.Research and practice in thrombosis and haemostasis · 2020Article
- The experience of postpartum bleeding in women with inherited bleeding disorders.Research and practice in thrombosis and haemostasis · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to evaluate the incidence of undiagnosed abnormal postpartum blood loss (UPPBL) after vaginal delivery, identify the risk factors and compare them to those of postpartum haemorrhage (PPH).
methodThe study population included women who participated in a randomized controlled trial of women with singleton low-risk pregnancy who delivered vaginally after 35 weeks' gestation (n = 3917). Clinical PPH was defined as postpartum blood loss ≥ 500 mL measured by using a collector bag and UPPBL was defined by a peripartum change in haemoglobin ≥ 2 g/dL in the absence of clinical PPH. Risk factors were assessed by multivariate multinomial logistic regression.
resultsThe incidence of UPPBL and PPH was 11.2% and 11.0% of vaginal deliveries, respectively. The median peripartum change in Hb level was comparable between UPPBL and PPH groups (2.5 g/dL interquartile range [2.2-3.0] and 2.4 g/dL IQR [1.5-3.3]). Risk factors specifically associated with UPPBL were Asian geographical origin (adjusted OR [aOR] 2.3, 95% confidence interval [CI] 1.2-4.2; p = 0.009), previous caesarean section (aOR 3.4, 2.1-5.5; p<0.001) and episiotomy (aOR 2.6, 1.8-3.6; p<0.001). Risk factors for both UPPBL and PPH were primiparity, long duration of labour, instrumental delivery and retained placenta.
conclusionUndiagnosed abnormal postpartum blood loss is frequent among women giving birth vaginally and has specific risk factors. The clinical importance of this entity needs further confirmation, and the benefit of systematic or targeted prevention strategies needs to be assessed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.