Evidence map›Paper›PMID 29320540›Full record

Observational studyPloS one2018

Discerning suicide in drug intoxication deaths: Paucity and primacy of suicide notes and psychiatric history.

Ian R H Rockett, Eric D Caine, Hilary S Connery, Gail D'Onofrio, David J Gunnell, Ted R Miller, Kurt B Nolte, Mark S Kaplan, Nestor D Kapusta, Christa L Lilly and 6 more

Abstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Association between undetermined intent death classification and county death investigation system for drug poisoning deaths in nine US jurisdictions.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2026
    Article
  4. Article
  5. Article
  6. Racial/ethnic inequality in homelessness and drug overdose deaths in US States.Social psychiatry and psychiatric epidemiology · 2025
    Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ian R H RockettDepartment of Epidemiology, West Virginia University, Morgantown, West Virginia, United States of America.ORCID 0000-0002-4584-9337
Eric D CaineDepartment of Psychiatry, University of Rochester Medical Center, Rochester, New York, United States of America.
Hilary S ConneryDivision of Alcohol and Drug Abuse, McLean Hospital, Boston, Massachusetts, United States of America.
Gail D'OnofrioDepartment of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America.
David J GunnellSchool of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.
Ted R MillerPacific Institute for Research and Evaluation, Calverton, Maryland, United States of America.
Kurt B NolteOffice of the Medical Investigator, University of New Mexico School of Medicine, Albuquerque, New Mexico, United States of America.
Mark S KaplanUCLA Luskin School of Public Affairs, Los Angeles, California, United States of America.
Nestor D KapustaDepartment of Psychoanalysis and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Christa L LillyDepartment of Biostatistics, West Virginia University, Morgantown, West Virginia, United States of America.
Lewis S NelsonDepartment of Emergency Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, United States of America.
Sandra L PutnamInjury Control Research Center, West Virginia University, Morgantown, West Virginia, United States of America.
Steven StackDepartment of Criminal Justice, Wayne State University, Detroit, Michigan, United States of America.
Peeter VärnikEstonian-Swedish Mental Health and Suicidology Institute, Tallinn, Estonia.
Lynn R WebsterPRA Health Sciences, Salt Lake City, Utah, United States of America.
Haomiao JiaDepartment of Biostatistics, Columbia University, New York, New York, United States of America.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Sally Lynn Hodder · 2012 to 2026
$81.0M
ACL HHS R49CE002093ACL HHS R49CE002109NCATS NIH HHS UL1 TR001863NCIPC CDC HHS R49 CE002093NCIPC CDC HHS R49 CE002109NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

objectiveA paucity of corroborative psychological and psychiatric evidence may be inhibiting detection of drug intoxication suicides in the United States. We evaluated the relative importance of suicide notes and psychiatric history in the classification of suicide by drug intoxication versus firearm (gunshot wound) plus hanging/suffocation-the other two major, but overtly violent methods.

methodsThis observational multilevel (individual/county), multivariable study employed a generalized linear mixed model (GLMM) to analyze pooled suicides and undetermined intent deaths, as possible suicides, among the population aged 15 years and older in the 17 states participating in the National Violent Death Reporting System throughout 2011-2013. The outcome measure was relative odds of suicide versus undetermined classification, adjusted for demographics, precipitating circumstances, and investigation characteristics.

resultsA suicide note, prior suicide attempt, or affective disorder was documented in less than one-third of suicides and one-quarter of undetermined deaths. The prevalence gaps were larger among drug intoxication cases than gunshot/hanging cases. The latter were more likely than intoxication cases to be classified as suicide versus undetermined manner of death (adjusted odds ratio [OR], 41.14; 95% CI, 34.43-49.15), as were cases documenting a suicide note (OR, 33.90; 95% CI, 26.11-44.05), prior suicide attempt (OR, 2.42; 95% CI, 2.11-2.77), or depression (OR, 1.61; 95% CI, 1.38 to 1.88), or bipolar disorder (OR, 1.41; 95% CI, 1.10-1.81). Stratification by mechanism/cause intensified the association between a note and suicide classification for intoxication cases (OR, 45.43; 95% CI, 31.06-66.58). Prior suicide attempt (OR, 2.64; 95% CI, 2.19-3.18) and depression (OR, 1.48; 95% CI, 1.17-1.87) were associated with suicide classification in intoxication but not gunshot/hanging cases.

conclusionsWithout psychological/psychiatric evidence contributing to manner of death classification, suicide by drug intoxication in the US is likely profoundly under-reported. Findings harbor adverse implications for surveillance, etiologic understanding, and prevention of suicides and drug deaths.

Indexed as

IntentionAdolescentAdultAgedAsphyxiaCause of DeathDepressionDrug OverdoseFemaleHumansMaleMedical RecordsMethodsMiddle AgedMood DisordersPopulation Surveillance

Identifiers

PMID29320540
PMCPMC5761891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.