Evidence map›Paper›PMID 29320445›Full record

ArticleMolecules (Basel, Switzerland)2018

Chlorophyll-Inspired Red-Region Fluorophores: Building Block Synthesis and Studies in Aqueous Media.

Rui Liu, Mengran Liu, Don Hood, Chih-Yuan Chen, Christopher J MacNevin, Dewey Holten, Jonathan S Lindsey

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rui LiuDepartment of Chemistry, North Carolina State University, Raleigh, NC 27695-8204, USA. rliu8@ncsu.edu.
Mengran LiuDepartment of Chemistry, North Carolina State University, Raleigh, NC 27695-8204, USA. mliu5@ncsu.edu.
Don HoodDepartment of Chemistry, Washington University, St. Louis, MO 63130-4889, USA. hoodlaw@sbcglobal.net.
Chih-Yuan ChenNIRvana Sciences, Inc., Research Triangle Park, NC 27709, USA.
Christopher J MacNevinNIRvana Sciences, Inc., Research Triangle Park, NC 27709, USA. chris@nirvanasciences.com.
Dewey HoltenDepartment of Chemistry, Washington University, St. Louis, MO 63130-4889, USA. holten@wustl.edu.
Jonathan S LindseyDepartment of Chemistry, North Carolina State University, Raleigh, NC 27695-8204, USA. jlindsey@ncsu.edu.ORCID 0000-0002-4872-2040

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorophores that absorb and emit in the red spectral region (600-700 nm) are of great interest in photochemistry and photomedicine. Eight new target chlorins (and 19 new chlorins altogether)-analogues of chlorophyll-of different polarities have been designed and synthesized for various applications; seven of the chlorins are equipped with a bioconjugatable tether. Hydrophobic or amphiphilic chlorins in a non-polar organic solvent (toluene), polar organic solvent (DMF), and aqueous or aqueous micellar media show a sharp emission band in the red region and modest fluorescence quantum yield (Φ

Indexed as

AvidinChlorophyllFluorescenceFluorescent DyesHydrophobic and Hydrophilic InteractionsMagnetic Resonance SpectroscopyMass SpectrometryMicellesMolecular StructurePhotochemistryPolyethylene GlycolsPorphyrinsSolventsStructure-Activity RelationshipSurface PropertiesWaterAvidinchlorinChlorophyllFluorescent DyesMicellesPolyethylene GlycolsPorphyrinsSolventsWateramphiphilicbioconjugationchlorinfluorescencemicellePEGPoissonprotein

Identifiers

PMID29320445
PMCPMC6017558

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.