ArticleAllergy2018
Usefulness of asthma predictive index in ascertaining asthma status of children using medical records: An explorative study.
Article in Allergy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Precision medicine to diagnose asthma in preschool children: comparison of clinical scores, lung function, biomarkers, and genetic tests.Paediatric respiratory reviews · 2026Review
- Early initiation of inhaled corticosteroid-long-acting βPediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026Article
- Feasibility and acceptability of a passive digital marker for childhood asthma risk prognosis: a pilot cross-sectional study.Pilot and feasibility studies · 2026Article
- Diagnosis and management of asthma in infants and preschoolers.Clinical and experimental pediatrics · 2022Article
- Serum Periostin Predicts Wheezing Exacerbation: A Prospective Study in Preschool Children with Recurrent Wheezing.International archives of allergy and immunology · 2022Article
- A pilot study to evaluate the role of circulation CD4BMC pediatrics · 2021Article
- A Pediatric Asthma Risk Score to better predict asthma development in young children.The Journal of allergy and clinical immunology · 2019Article
- Early Identification of Childhood Asthma: The Role of Informatics in an Era of Electronic Health Records.Frontiers in pediatrics · 2019Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundFrequent wheezing in original asthma predictive index (API) was defined by parental report of recurrent wheezing within 1 year during the first 3 years of life. The nature of frequent wheezing in children, particularly aged over 3 years, has not been studied. We aimed to assess the frequency and interval of wheezing to define frequent wheezing in ascertaining asthma for children using medical records.
methodsAmong children who participated in a previous study (n = 427), all wheezing episodes documented in medical records were collected for children who had ≥2 wheezing episodes PLUS met one major criterion or two minor criteria of API. We compared the distribution of known risk factors for asthma between subjects having two consecutive wheezing episodes with shorter interval (≤1 year) compared to those with longer interval (1 to 3 years).
resultsA total of 62 children met API at median age of 2.3 years. During follow-up period (median age: 11.3 years), a total of 198 wheezing episodes were observed. 81% of wheezing intervals were within 3 years from the earlier wheezing episode, including 60% within 1 year. Children who met API based on 1-year interval (n = 40) vs 1- to 3-year interval (n = 13) appeared to be similar in regard to the known risk factors for asthma.
conclusionsOur exploratory study finding suggests that children who had frequent wheezing episodes with longer interval (<3 years) need to be considered to be determined as asthma cases when API is applied to retrospective medical records. Prospective studies with a larger sample size need to replicate this finding.
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