ArticleClinics (Sao Paulo, Brazil)2017
Effects of periarticular injection on analgesic effects and NSAID use in total knee arthroplasty and total hip arthroplasty.
Article in Clinics (Sao Paulo, Brazil), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05898581 (Ultrasound-guided Pericapsular Nerve Group), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ultrasound-guided Pericapsular Nerve Group (PENG) Block vs. Intraoperative Local Anesthetic Infiltration (ILAI) for Total Hip Arthroplasty (THA): a Single Center, Non-inferiority Randomized Control Trial Pilot Study.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Comparative efficacy of analgesic techniques in total hip arthroplasty : a systematic review and network meta-analysis of more than 100 randomized studies incorporating minimal clinically important difference.Bone & joint open · 2026Pooled it
- The efficacy of intraoperative periarticular injection in Total hip arthroplasty: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2019Pooled it
- Proximal tibia osteotomy with absorbable spacer combined with fibular osteotomy versus high tibial osteotomy for medial compartmental knee osteoarthritis.International orthopaedics · 2023Trial
- Comparison of efficacy between combined periarticular and incisional injections versus periarticular injection alone of bupivacaine for pain control after total knee arthroplasty: A prospective randomized controlled trial.Acta orthopaedica et traumatologica turcica · 2020Trial
- Do Adductor Canal Blocks Provide Additional Analgesic Benefit to Periarticular Injection Alone for Primary Total Knee Arthroplasty?Arthroplasty today · 2026Article
- Postoperative Pain Management Strategies Without Regional Analgesia in Knee Surgeries: A Scoping Review.Medical sciences (Basel, Switzerland) · 2026Article
- Comparative Efficacy of Periarticular Fentanyl versus Ketorolac for Postoperative Pain in Total Hip Arthroplasty: A Randomized Controlled Trial.Journal of orthopaedic case reports · 2025Article
- Comparative Study of Functional Outcome and Pain Control with Non-steroidal Anti-inflammatory Drugs (NSAIDs) and Non-NSAIDs in Early Post-operative Period in Total Knee Arthroplasty.Journal of orthopaedic case reports · 2025Article
- Artificial intelligence technology and ultrasound-guided nerve block for analgesia in total knee arthroplasty.World journal of clinical cases · 2023Article
- Efficacy of Periarticular Local Infiltrative Analgesic Injection on Postoperative Pain Control and Functional Outcome in Sequential Bilateral Total Knee Replacement: A Prospective Controlled Trial in 120 Consecutive Patients.Indian journal of orthopaedics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study examined periarticular multimodal drug injection and the use of nonsteroidal anti-inflammatory drugs for an early analgesic effect after total knee arthroplasty and total hip arthroplasty. Patient satisfaction and benefits from the treatment were also assessed.
methodsA total of 110 patients who were scheduled to undergo total knee arthroplasty and 86 patients who were scheduled to undergo total hip arthroplasty were divided into two groups, the study group and the control group. The study group received a periarticular multimodal drug injection during surgery. The control group received an equal volume of normal saline. All patients received an analgesia pump and a moderate dose of nonsteroidal anti-inflammatory drugs. Resting and motion Numeric Rating Scale scores, the Western Ontario and McMaster Universities Arthritis Index, knee or hip joint range of motion, length of postoperative hospital stay, patient satisfaction, total nonsteroidal anti-inflammatory drug consumption and side effects were recorded.
resultsBoth study groups exhibited significant improvement in pain Numeric Rating Scale scores during rest and exercise several days after the surgery. The range of joint motion was greater in the study group, and the length of postoperative hospital stay was shorter than that in the control group. Patients in the study group consumed fewer nonsteroidal anti-inflammatory drugs and reported greater satisfaction with surgery.
conclusionIntraoperative periarticular multimodal drug injection significantly relieved pain after surgery and reduced nonsteroidal anti-inflammatory drug consumption. These patient had a better postoperative experience, including satisfaction and rehabilitation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.