Evidence map›Paper›PMID 29319406›Full record

ArticleNeurodegenerative disease management2018

Completed suicide in an autopsy-confirmed case of early onset Alzheimer's disease.

Jennifer Wiener Hartzell, Richard Geary, Kymberly Gyure, Venkata Ravi Chivukula, Marc W Haut

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Neurodegenerative disease management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jennifer Wiener HartzellDepartment of Supportive Oncology, Levine Cancer Institute, Carolinas HealthCare System, NC 28202, USA.
Richard GearyDepartment of Psychiatry, Overlake Medical Center, WA 98004, USA.
Kymberly GyureDepartment of Pathology, West Virginia University School of Medicine, WV 26506, USA.
Venkata Ravi ChivukulaDepartment of Behavioral Medicine & Psychiatry, West Virginia University School of Medicine, WV 26505, USA.
Marc W HautDepartment of Neurology, West Virginia University School of Medicine, WV 26506, USA.
West Virginia University · USLevine Cancer Institute · USOverlake Hospital Medical Center · US

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Sally Lynn Hodder · 2012 to 2026
$81.0M
West Virginia University Stroke COBREP20GM109098 · NIGMS · WEST VIRGINIA UNIVERSITY · PI DEVRIES, ANNE COURTNEY · 2014 to 2024
$24.5M
Customized cortical stimulation therapy in the rehabilitation of stroke patientsR01NS090677 · NINDS · EMORY UNIVERSITY · PI BUETEFISCH, CATHRIN M · 2015 to 2018
$3.0M
NIGMS NIH HHS P20 GM109098NIGMS NIH HHS U54 GM104942NIH HHS 1R01NS090677-01NINDS NIH HHS R01 NS090677
6 · The paper itself

Abstract

We report a case of a 57-year-old male with clinically diagnosed and autopsy-confirmed early onset Alzheimer's disease who completed suicide by gunshot wound to the chest. This case has several unique aspects that have not been discussed in previous case reports of completed suicide in Alzheimer's disease. In particular, our patient's death was highly planned with successful compensation for his cognitive deficits. After all firearms had been removed from the home as a safety precaution, he obtained a new weapon, hid it and left himself cues to find and use it. The case is discussed in the context of literature differentiating the neural circuitry propagating impulsive versus planned suicidal acts.

Indexed as

SuicideAlzheimer DiseaseAutopsyBrainFollow-Up StudiesHumansMagnetic Resonance ImagingMaleMental Status ScheduleMiddle AgedAlzheimer’s diseaseearly onsetsuicide

Identifiers

PMID29319406
PMCPMC6367712
OpenAlexW2783960328

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.