Evidence map›Paper›PMID 29319161›Full record

ArticleJournal of cellular physiology2018

Anticancer and antibacterial effects of Iranian viper (Vipera latifii) venom; an in-vitro study.

Abdullah Moridikia, Jamil Zargan, Hossein Sobati, Hamid R Goodarzi, Ashkan Hajinourmohamadi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Genotoxic Activity ofBiology · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Comparison of Methods for Measuring Protein Concentration in Venom Samples.Animals : an open access journal from MDPI · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Abdullah MoridikiaChemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0003-0777-0860
Jamil ZarganScience Biology Research Center, Imam Hussein University, Tehran, Iran.
Hossein SobatiHealth Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Hamid R GoodarziCentral Laboratory, Razi Vaccine and Serum Research Institute, Agricultural education, Research and Extension Organization, Tehran, Iran.
Ashkan HajinourmohamadiImam Hossein University, Tehran, Iran.
Imam Hossein University · IRBaqiyatallah University of Medical Sciences · IRRazi Vaccine and Serum Research Institute · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viper venom contains antibacterial and cytotoxic components. The aim of this study was to identify and evaluate the antimicrobial and cytotoxic properties of the crude venom of Vipera latifii (V. latifii). Lyophilized venom of V. latifii was quantified by Bradford method and its antibacterial activity (6.25-400 μg/ml) was assessed using the MTT, MIC, Disc diffusion, and Well diffusion assays. Also, its cytotoxic activity was investigated using MTT reduction, Neutral uptake, and Comet assay on human liver cancer (HepG2) cell line. Crude venom showed antibacterial effects against Bacillus subtilis and Staphylococcus aureus, but was not effective on Escherichia coli. Also, the crude venom showed apoptotic and necrotic effects on human liver cancer cells. The venom of V. latifii can inhibit the growth of bacteria and cancer cells. These findings suggest that this may be a potential source of molecules with antibacterial and anticancer characteristics.

Indexed as

AnimalsAnti-Bacterial AgentsAntineoplastic AgentsBacillus subtilisCell Line, TumorEscherichia coliHep G2 CellsHumansIranSnakesStaphylococcus aureusViper VenomsAnti-Bacterial AgentsAntineoplastic AgentsViper VenomsantibacterialcytotoxicsnakevenomVipera latifii

Identifiers

PMID29319161
PMCPMC13482410
OpenAlexW2782618153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.