Evidence map›Paper›PMID 29318868›Full record

Trial reportJBRA assisted reproduction2018

Embryo development until blastocyst stage with and without renewal of single medium on day 3.

Fernando Peña, Rocío Dávalos, Adolfo Rechkemmer, Alvaro Ascenzo, Mauricio Gonzales

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in JBRA assisted reproduction, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04969575 (Exploring Single Step Culture Medium Refreshment Effect on Embryo Ploidy Rate), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04969575 unknown statusnot on this mapstarted 2021, after this paper: background citation

Exploring Single Step Culture Medium Refreshment Effect on Embryo Ploidy Rate: A Benchtop Incubator Prospective Study

TypeobservationalSponsorART Fertility Clinics LLCRan2021 to 2023Enrolled50ConditionsInfertilityArmsInsemination and culture, Media refreshment Group 1, Culture media preparation and refreshment, Embryo grading, Media refreshment Group 2
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fernando PeñaLaboratorio de Reproducción Asistida, Clínica Miraflores, Lima, Peru.
Rocío DávalosLaboratorio de Reproducción Asistida, Clínica Miraflores, Lima, Peru.
Adolfo RechkemmerLaboratorio de Reproducción Asistida, Clínica Miraflores, Lima, Peru.
Alvaro AscenzoLaboratorio de Reproducción Asistida, Clínica Miraflores, Lima, Peru.
Mauricio GonzalesLaboratorio de Biotecnología Animal, Facultad de Ciencias, Universidad Ricardo Palma, Lima, Peru.
Universidad Ricardo Palma · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to assess the effects of using a single culture medium not renewed on day 3 on the development of the embryo up to the blastocyst stage.

methodsThe study was carried out in the Assisted Reproduction Laboratory of Clínica Miraflores in the period ranging from April to December of 2016. The study included 589 human embryos obtained from 82 couples submitted to IVF/ICSI with donor oocytes. The couples were randomly divided into two groups: group 1 (medium renewed on day 3) and group 2 (medium not renewed on day 3).

resultsSignificant differences in pregnancy rates, implantation rates, and blastocyst formation were not observed.

conclusionNo statistically significant difference was found between the groups with respect to the analyzed parameters. However, a non-significant trend was observed in favor of the group without medium renewal for clinical pregnancy and positive pregnancy rates (β-hCG).

Indexed as

Fertilization in VitroBlastocystCells, CulturedCleavage Stage, OvumCulture MediaEmbryo Culture TechniquesEmbryo, MammalianEmbryonic DevelopmentEmbryo TransferFemaleHumansInfant, NewbornMalePregnancyPregnancy RateTime FactorsCulture MediaEmbryo culturesingle mediumuninterrupted culturewith and without culture renewal

Identifiers

PMID29318868
PMCPMC5844659
OpenAlexW2783988060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.