Evidence map›Paper›PMID 29318612›Full record

ArticleEuropean journal of immunology2018

Transplanted human thymus slices induce and support T-cell development in mice after cryopreservation.

Susan Ross, Melissa Cheung, Ching-In Lau, Neil Sebire, Michael Burch, Peter Kilbride, Barry Fuller, G John Morris, E Graham Davies, Tessa Crompton

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Reconstitution of thymopoiesis via implantation of cryopreserved cultured thymus tissue into athymic recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
    Article
  3. Article
  4. A model for preservation of thymocyte-depleted thymus.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Susan RossUCL Great Ormond Street Institute of Child Health, London, UK.
Melissa CheungUCL Great Ormond Street Institute of Child Health, London, UK.
Ching-In LauUCL Great Ormond Street Institute of Child Health, London, UK.
Neil SebireGreat Ormond Street Hospital, London, UK.
Michael BurchGreat Ormond Street Hospital, London, UK.
Peter KilbrideAsymptote Ltd, Sovereign House, Vision Park, Cambridge, UK.
Barry FullerUCL Division of Surgery and Interventional Science, Royal Free Hospital Campus, London, UK.
G John MorrisAsymptote Ltd, Sovereign House, Vision Park, Cambridge, UK.
E Graham DaviesUCL Great Ormond Street Institute of Child Health, London, UK.
Tessa CromptonUCL Great Ormond Street Institute of Child Health, London, UK.ORCID 0000-0002-8973-4021

Funding

Biotechnology and Biological Sciences Research Council BB/I026324/1Wellcome TrustWellcome Trust WT094255MF
6 · The paper itself

Abstract

Nude mouse human thymus transplant model: Fresh or cryopreserved and thawed human thymus slices were transplanted subcutaneously into recipient nude mice. Nude mice subsequently produced mouse CD3

Indexed as

AnimalsCD4-Positive T-LymphocytesCell ProliferationCryopreservationHumansLymphocyte CountMiceMice, NudeThymus GlandTransplantation, HeterologousClinical immunologyCryopreservationThymopoiesisThymus transplantationTransplantation

Identifiers

PMID29318612
PMCPMC5947170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.