Evidence map›Paper›PMID 29318599›Full record

ReviewDevelopment, growth & differentiation2018

Mechanisms of kinetochore-microtubule attachment errors in mammalian oocytes.

Tomoya S Kitajima

Abstract readReview
In one paragraph

Review in Development, growth & differentiation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  9. Article
  10. Article
  11. Review
  12. Article
  13. Tubulin post-translational modifications in meiosis.Seminars in cell & developmental biology · 2023
    Review
  14. Centromere drive: model systems and experimental progress.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2022
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Tomoya S KitajimaLaboratory for Chromosome Segregation, RIKEN Center for Developmental Biology, Kobe, 650-0047, Japan.ORCID http://orcid.org/0000-0002-6486-7143

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proper kinetochore-microtubule attachment is essential for correct chromosome segregation. Therefore, cells normally possess multiple mechanisms for the prevention of errors in kinetochore-microtubule attachments and for selective stabilization of correct attachments. However, the oocyte, a cell that produces an egg through meiosis, exhibits a high frequency of errors in kinetochore-microtubule attachments. These attachment errors predispose oocytes to chromosome segregation errors, resulting in aneuploidy in eggs. This review aims to provide possible explanations for the error-prone nature of oocytes by examining key differences among other cell types in the mechanisms for the establishment of kinetochore-microtubule attachments.

Indexed as

AneuploidyMeiosisAnimalsFemaleHumansKinetochoresMammalsMicrotubulesOocytesaneuploidychromosome segregationkinetochoremicrotubuleoocyte

Identifiers

PMID29318599
PMCPMC11520954

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.