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ReviewGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2018

Optical coherence tomography angiography: a review of current and future clinical applications.

Marcus Ang, Anna C S Tan, Chui Ming Gemmy Cheung, Pearse A Keane, Rosa Dolz-Marco, Chelvin C A Sng, Leopold Schmetterer

Abstract readReview
PubMed Publisher
In one paragraph

Review in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed.

  1. [Optical coherence tomography angiography image segmentation based on multi-scale dilated convolution and dual attention network].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Article
  2. Review
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  8. Enhanced Imaging of Ocular Surface Lesions.Journal of clinical medicine · 2025
    Review
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  11. Impact of preocular and ocular circulatory dynamics on the vascular density of retinal capillary plexuses and choriocapillaris.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Observational
  12. Review
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  18. Seeing is believing: The development of optical coherence tomography.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  19. Article
  20. Review

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marcus AngSingapore National Eye Centre, 11 Third Hospital Avenue, Singapore, 168751, Singapore. marcus.ang@snec.com.sg.ORCID http://orcid.org/0000-0003-3022-0795
Anna C S TanSingapore National Eye Centre, 11 Third Hospital Avenue, Singapore, 168751, Singapore.
Chui Ming Gemmy CheungSingapore National Eye Centre, 11 Third Hospital Avenue, Singapore, 168751, Singapore.
Pearse A KeaneMoorfields Eye Hospital, London, UK.
Rosa Dolz-MarcoFISABIO Ophthalmic Medicine, Valencia, Spain.
Chelvin C A SngSingapore Eye Research Institute, Singapore, Singapore.
Leopold SchmettererDuke-NUS Medical School, Singapore, Singapore.

Funding

Department of Health CS-2014-14-023
6 · The paper itself

Abstract

Optical coherence tomography angiography is a non-invasive imaging technique that now allows for simultaneous in vivo imaging of the morphology as well as the vasculature in the eye. In this review, we provide an update on the existing clinical applications of optical coherence tomography angiography technology from the anterior to posterior segment of the eye. We also discuss the limitations of optical coherence tomography angiography technology, as well as the caveats to the interpretation of images. As current optical coherence tomography angiography systems are optimized for the retina, most studies have focused on interpreting images from conditions such as age related macular degeneration and retinal vascular diseases. However, the interpretation of these optical coherence tomography angiography images should be taken in consideration with other multi-modal imaging to overcome the limitations of each technique. In addition, there are a growing variety of clinical applications for optical coherence tomography angiography imaging in optic nerve head evaluation for glaucoma and optic neuropathies. Further developments in anterior optical coherence tomography angiography have now allowed for evaluation of anterior segment pathology such as glaucoma, ocular surface diseases, corneal vascularisation, and abnormal iris vasculature. Future developments in software could allow for improved segmentation and image resolution with automated measurements and analysis.

Indexed as

Eye DiseasesFluorescein AngiographyFundus OculiHumansReproducibility of ResultsTomography, Optical CoherenceAngiographyCorneaGlaucomaOptical coherence tomographyRetinaVascularisation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.